Results 51 to 60 of about 2,761 (153)

Severity bands for atopic dermatitis measures: Analysis from adult dupilumab randomized clinical trials

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1218-1226, July 2026.
This analysis used a large clinical trial data set (>30,000 patient visits across >2800 patients) and novel statistical methodologies (including frequency cross‐over analysis and means based on spline regression) to develop severity threshold bands for clinician‐ and patient‐reported outcome measures for adults with moderate‐to‐severe atopic dermatitis.
Andreas Wollenberg, Eric L. Simpson, Yael A. Leshem, Alain Taïeb, Norito Katoh, Jingdong Chao, Ana B. Rossi, Amy H. Praestgaard   +7 more
wiley   +1 more source

Validation of the Measure of Case‐Discussion Complexity and the Metric for the Observation of Decision‐Making for Streamlining Workflow and Evaluating Decision‐Making in US Tumor Boards

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Clinical guidelines for cancer care recognize multidisciplinary tumor boards (MTBs) as a gold standard for providing quality of care for cancer patients. However, the requirements and workflow for MTBs varies across countries, influencing their roles in decision making, care efficiency, and medical education.
T. Soukup, N. Lajmi, M. S. Prime, B. W. Lamb, W. Zhang, G. Markollari, R. Ortiz, S. Perrigo, K. Stuart, M. Wallace, K. Noyes, R. D. Hammer   +11 more
wiley   +1 more source

Improved Secure Integer Comparison via Homomorphic Encryption [PDF]

, 2019
Secure integer comparison has been one of the first problems introduced in cryptography, both for its simplicity to describe and for its applications.
Jacques Traoré, Olivier Sanders, Florian Bourse   +2 more
core   +1 more source

Better GBFV Bootstrapping and Faster Encrypted Edit Distance Computation [PDF]

We propose a new iterative method to convert a ciphertext from the Generalized BFV (GBFV) to the regular BFV scheme. In particular, our conversion starts from an encrypted plaintext that lives in a large cyclotomic ring modulo a small-norm polynomial $t ...
Robin Geelen, Frederik Vercauteren
core   +3 more sources

Deciphering nodal burden in thyroid carcinoma: A dedicated survey of age, lymph node ratio, log odds of positive nodes, and preoperative prediction models

Journal of Intelligent Medicine, Volume 3, Issue 2, Page 169-191, June 2026.
Abstract Evidence regarding the prognosis of thyroid carcinoma is heterogeneous, ranging from age effects and nodal burden metrics, such as lymph node ratio (LNR) and log odds of positive nodes (LODDS), to preoperative imaging models comprising ultrasound, CEUS, and radiomics.
Mennatallah Sherif, Mohanad A. Deif, Eman K. Elsayed   +2 more
wiley   +1 more source

Sample Size Calculation for the ROCI Design

Statistics in Medicine, Volume 45, Issue 13-14, June 2026.
ABSTRACT The Response Over Continuous Intervention (ROCI) design offers a number of potential benefits over conventional non‐inferiority trials in studies focused on the late‐phase optimization of a continuous aspect of treatment intervention. One possible application of this design is in de‐escalation trials, which aim to reduce the dose, duration, or
Henry Bern, James Carpenter, Mahesh Parmar, Ian R. White, Matteo Quartagno   +4 more
wiley   +1 more source

Fast Estimation and Valid Statistical Inference for Mixed‐Effect Location‐Scale Models Using Variational Inference

Statistics in Medicine, Volume 45, Issue 13-14, June 2026.
ABSTRACT With the development of modern technology, richer and more intensive longitudinal data are available for researchers to study more complex model structures. The Mixed‐Effect Location‐Scale Model (MELS) is useful for modeling the variance components in such data.
Brian Ping‐Huan Wu, Donald Hedeker
wiley   +1 more source

Robust optimization in simulation: Taguchi and Krige combined [PDF]

, 2011
Optimization of simulated systems is the goal of many methods, but most methods assume known environments. We, however, develop a "robust" methodology that accounts for uncertain environments.
Jack P. C. Kleijnen, Carlo Meloni, Dellino, Gabriella, Gabriella Dellino, Meloni, Carlo, Kleijnen, J. P. C., Kleijnen, Jack P.C., Dellino, G., Kleijnen, Jack P.C.; id_orcid, Meloni, C.   +9 more
core   +1 more source

A New Strategy for Improving Multi‐Frequency PPP‐RTK Ionospheric Correction Availability and User Performance in Low‐ and Middle‐Latitudes

Journal of Geophysical Research: Space Physics, Volume 131, Issue 6, June 2026.
Abstract High‐precision regional ionospheric correction products are essential for achieving accurate and fast‐convergence solutions in Precise Point Positioning Real‐Time Kinematic (PPP‐RTK). For users in low‐ and middle‐latitudes, PPP‐RTK server narrow‐lane (NL) ambiguity resolution (AR) typically requires more than 10 min, which largely affects the ...
Pan Li, Shitong Chen, Jiahuan Hu, Xin Xie, Jiadi Dai, Bao Shu, Guanwen Huang   +6 more
wiley   +1 more source

Validation of machine learning based scenario generators

Journal of Risk and Insurance, Volume 93, Issue 2, Page 508-533, June 2026.
Abstract Machine learning (ML) methods are becoming increasingly important for designing economic scenario generators for internal models. Validating data‐driven models requires different methods than validating classical, theory‐based models. We discuss two novel aspects of such validation: first, checking the multivariate distribution of risk factors,
Gero Junike, Solveig Flaig, Ralf Werner
wiley   +1 more source