Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan +10 more
wiley +1 more source
Analytical solutions and dynamic behavior of conformable fractional reaction-diffusion systems. [PDF]
Alshehry AS, Shah R, Alqahtani AM.
europepmc +1 more source
A unified Haar wavelet collocation framework for fractional volterra integro-differential equations with application to tumor-immune dynamics modeling. [PDF]
Hamood MM, Sharif AA, Ghadle KP.
europepmc +1 more source
Fractional spatiotemporal Hahnfeldt tumor model with convergence analysis and optimal control. [PDF]
Can E.
europepmc +1 more source
On the size of integer solutions of elliptic equations
Y. Bugeaud
semanticscholar +1 more source
Research on a fuzzy programming model and algorithm for berth allocation considering time-varying water depth. [PDF]
Liu D, Li B, Li M, Lei Y, Yu P, Tan C.
europepmc +1 more source
Generalized fractional modeling and optimal control of respiratory syncytial virus infections in Florida. [PDF]
Jajarmi A.
europepmc +1 more source
Modeling of fractional order DPG model insight global warming and pollution effect on desertification for control mechanism. [PDF]
Farman M +6 more
europepmc +1 more source
Computational framework and machine learning approach to fractional order soil helminth infections disease model for control mechanism. [PDF]
Nisar KS +4 more
europepmc +1 more source
ABSTRACT In order to reflect the actual production situation more comprehensively and optimize the production cost, this paper solves the short‐term scheduling optimization problem for a single pipeline containing high melting point crude oil. Based on the refining plan given by the upper layer, a multi‐objective optimization model with high melting ...
Jing Yao +5 more
wiley +1 more source

