Results 51 to 60 of about 4,441 (247)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Lietuvos Matematikos Rinkinys, 2004 Parabolic (φ, ξ, η, λ)-structures and parabolic metric (φ, ξ, η, g, λ)-structures on hypersurfaces of parabolic integrable F-manifolds and parabolic integrable (F, G)-manifolds, respectively, are regarded.
Angelė Baškienė
doaj +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A Fast Algorithmic Way to Calculate the Degree Growth of Birational Mappings
MathematicsWe present an algorithmic method for the calculation of the degrees of the iterates of birational mappings based on Halburd’s method for obtaining the degrees from the singularity structure of the mapping.
Basil Grammaticos +3 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
On Transformations of the Rabelo Equations
Symmetry, Integrability and Geometry: Methods and Applications, 2007 We study four distinct second-order nonlinear equations of Rabelo which describe pseudospherical surfaces. By transforming these equations to the constant-characteristic form we relate them to some well-studied integrable equations.
Anton Sakovich, Sergei Sakovich
doaj
INTEGRATION – WHAT INTEGRATION?
European Societies, 2012 ABSTRACT Since the founding of the European Union, religion has become an increasingly important aspect in shaping European identity and thereby social cohesion in Europe. Social cohesion depends to a high degree on a successfully established distinction between ‘us’ and ‘them’.
Florian Grötsch, Annette Schnabel
openaire +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Integrability for Solutions of Anisotropic Obstacle Problems
International Journal of Mathematics and Mathematical Sciences, 2012 This paper deals with anisotropic obstacle problem for the 𝒜-harmonic equation ∑i=1nDi(ai(x,Du(x)))=0. An integrability result is given under suitable assumptions, which show higher integrability of the boundary datum, and the obstacle force solutions u ...
Hongya Gao, Yanjie Zhang, Shuangli Li
doaj +1 more source