Results 71 to 80 of about 1,065,720 (348)

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A Fast Algorithmic Way to Calculate the Degree Growth of Birational Mappings

open access: yesMathematics
We present an algorithmic method for the calculation of the degrees of the iterates of birational mappings based on Halburd’s method for obtaining the degrees from the singularity structure of the mapping.
Basil Grammaticos   +3 more
doaj   +1 more source

Quantum integrability of the deformed elliptic Calogero-Moser problem

open access: yes, 2004
The integrability of the deformed quantum elliptic Calogero-Moser problem introduced by Chalykh, Feigin and Veselov is proven. Explicit recursive formulae for the integrals are found.
Berezin F. A.   +5 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Normal and integrable parabolic metric (φ, ξ, η, g, λ)-structures on hypersurfaces of parabolic integrable (F , G)-manifolds

open access: yesLietuvos Matematikos Rinkinys, 2004
Parabolic (φ, ξ, η, λ)-structures and parabolic metric  (φ, ξ, η, g, λ)-structures on hypersurfaces of parabolic integrable F-manifolds and parabolic integrable (F, G)-manifolds, respectively, are regarded.
Angelė Baškienė
doaj   +3 more sources

On Transformations of the Rabelo Equations

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2007
We study four distinct second-order nonlinear equations of Rabelo which describe pseudospherical surfaces. By transforming these equations to the constant-characteristic form we relate them to some well-studied integrable equations.
Anton Sakovich, Sergei Sakovich
doaj  

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