Results 91 to 100 of about 26,470 (301)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Superstring Holography and Integrability in AdS₅ x S⁵ [PDF]

open access: yes, 2005
The AdS/CFT correspondence provides a rich testing ground for many important topics in theoretical physics. The earliest and most striking example of the correspondence is the conjectured duality between the energy spectrum of type IIB superstring ...
Swanson, Ian Jakov
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

On the variational structure of breather solutions II: periodic mKdV equation

open access: yesElectronic Journal of Differential Equations, 2017
We study the periodic modified KdV equation, where a periodic in space and time breather solution is known from the work of Kevrekidis et al.\ [19]. We show that these breathers satisfy a suitable elliptic equation, and we also discuss via numerics ...
Miguel A. Alejo   +2 more
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

A test in Asymptotic Integrability of 1 + 1 wave equations

open access: yes, 1998
We discuss a test for asymptotic integrability of 1+1 dispersive ...
A. Degasperis, PROCESI, MICHELA
core  

Symmetries and special solutions of reductions of the lattice potential KdV equation [PDF]

open access: yes, 2014
. We identify a periodic reduction of the non-autonomous lattice potential Korteweg–de Vries equation with the additive discrete Painlevé equation with E (1) 6 symmetry.
Christopher M. Ormerod, Ormerod, C.M.
core   +1 more source

Rational Involutions and an Application to Planar Systems of ODE

open access: yesMathematics
An involution refers to a function that acts as its own inverse. In this paper, our focus lies on exploring two-dimensional involutive maps defined by rational functions.
Ivan Mastev   +2 more
doaj   +1 more source

Integrability, non-integrability and confinement [PDF]

open access: yesJournal of Statistical Mechanics: Theory and Experiment, 2011
We discuss the main features of quantum integrable models taking the classes of universality of the Ising model and the repulsive Lieb-Liniger model as paradigmatic examples. We address the breaking of integrability by means of two approaches, the Form Factor Perturbation Theory and semiclassical methods. Each of them has its own advantage.
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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