Results 121 to 130 of about 4,761,670 (353)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

On the compatible weakly nonlocal Poisson brackets of hydrodynamic type

International Journal of Mathematics and Mathematical Sciences, 2002
We consider the pairs of general weakly nonlocal Poisson brackets of hydrodynamic type (Ferapontov brackets) and the corresponding integrable hierarchies.
Andrei Ya. Maltsev
doaj   +1 more source

New N $$ \mathcal{N} $$ = 2 superspace Calogero models

Journal of High Energy Physics, 2020
Starting from the Hamiltonian formulation of N $$ \mathcal{N} $$ = 2 supersymmetric Calogero models associated with the classical A n , B n , C n and D n series and their hyperbolic/trigonometric cousins, we provide their superspace description.
Sergey Krivonos, Olaf Lechtenfeld, Anton Sutulin   +2 more
doaj   +1 more source

Generalized Hirota bilinear identity and integrable q-difference and lattice hierarchies.

, 1995
Hirota bilinear identity for Cauchy-Baker-Akhieser (CBA) kernel is introduced as a basic tool to construct integrable hierarchies containing lattice and q-difference times.
Bogdanov, Bogdanov, Grinevich, L.V. Bogdanov, Miwa, Segal, Zakharov, Zakharov   +7 more
core   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Electric network and Hirota type 4-simplex maps

Journal of High Energy Physics
Bazhanov-Stroganov (4-simplex) maps are set-theoretical solutions to the 4-simplex equation, namely the fourth member of the family of n-simplex equations, which are fundamental equations of mathematical physics.
S. Konstantinou-Rizos
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Associativity equations in dispersionless integrable hierarchies

Physics Letters B, 2001
We discuss the origin of the associativity (WDVV) equations in the context of quasiclassical or Whitham hierarchies. The associativity equations are shown to be encoded in the dispersionless limit of the Hirota equations for KP and Toda hierarchies. We show, therefore, that any tau-function of dispersionless KP or Toda hierarchy provides a solution to ...
Boyarsky, A.M., Marshakov, A., Ruchayskiy, O., Wiegmann, P., Zabrodin, A.   +4 more
openaire   +3 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source