Results 71 to 80 of about 1,039 (297)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Lagrangian structures and multidimensional consistency [PDF]
, 2010 The conventional point of view is that the Lagrangian is a scalar object (or equivalently a volume form), which through the Euler-Lagrange equations provides us with one single equation (i.e., one per component of the dependent variable ...
Lobb, Sarah Beverley
core
Tau-functions and generalized integrable hierarchies
, 1992 The tau-function formalism for a class of generalized ``zero-curvature'' integrable hierarchies of partial differential equations, is constructed. The class includes the Drinfel'd-Sokolov hierarchies.
Hollowood, Timothy J. +2 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
From one to infinity: symmetries of integrable systems
Journal of High Energy PhysicsIntegrable systems constitute an essential part of modern physics. Traditionally, to approve a model is integrable one has to find its infinitely many symmetries or conserved quantities.
S. Y. Lou, Man Jia
doaj +1 more source
Quantum trace formulae for the integrals of the hyperbolic Ruijsenaars-Schneider model
Journal of High Energy Physics, 2019 We conjecture the quantum analogues of the classical trace formulae for the integrals of motion of the quantum hyperbolic Ruijsenaars-Schneider model.
Gleb Arutyunov +2 more
doaj +1 more source
The non-chiral intermediate Heisenberg ferromagnet equation
Journal of High Energy Physics, 2022 We present and solve a soliton equation which we call the non-chiral intermediate Heisenberg ferromagnet (ncIHF) equation. This equation, which depends on a parameter δ > 0, describes the time evolution of two coupled spin densities propagating on the ...
Bjorn K. Berntson +2 more
doaj +1 more source
A class of multidimensional integrable hierarchies and their reductions [PDF]
Theoretical and Mathematical Physics, 2009 A class of multidimensional integrable hierarchies connected with commutation of general (unreduced) (N+1)-dimensional vector fields containing derivative over spectral variable is considered. They are represented in the form of generating equation, as well as in the Lax-Sato form.
openaire +3 more sources
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source