Results 71 to 80 of about 137,094 (294)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Quantum trace formulae for the integrals of the hyperbolic Ruijsenaars-Schneider model

open access: yesJournal of High Energy Physics, 2019
We conjecture the quantum analogues of the classical trace formulae for the integrals of motion of the quantum hyperbolic Ruijsenaars-Schneider model.
Gleb Arutyunov   +2 more
doaj   +1 more source

$\mathcal D$-bundles and integrable hierarchies

open access: yesJournal of the European Mathematical Society, 2011
We study the geometry of \mathcal D - bundles —locally projective \mathcal D -modules—on algebraic curves, and apply them to ...
David Ben-Zvi, Thomas Nevins
openaire   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

From one to infinity: symmetries of integrable systems

open access: yesJournal of High Energy Physics
Integrable systems constitute an essential part of modern physics. Traditionally, to approve a model is integrable one has to find its infinitely many symmetries or conserved quantities.
S. Y. Lou, Man Jia
doaj   +1 more source

The non-chiral intermediate Heisenberg ferromagnet equation

open access: yesJournal of High Energy Physics, 2022
We present and solve a soliton equation which we call the non-chiral intermediate Heisenberg ferromagnet (ncIHF) equation. This equation, which depends on a parameter δ > 0, describes the time evolution of two coupled spin densities propagating on the ...
Bjorn K. Berntson   +2 more
doaj   +1 more source

Nonassociativity and Integrable Hierarchies

open access: yes, 2005
Let A be a nonassociative algebra such that the associator (A,A^2,A) vanishes. If A is freely generated by an element f, there are commuting derivations delta_n, n=1,2,..., such that delta_n(f) is a nonlinear homogeneous polynomial in f of degree n+1. We prove that the expressions delta_{n_1} ...
Dimakis, Aristophanes   +1 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A note on gl2 $$ \mathfrak{g}{\mathfrak{l}}_2 $$-invariant Bethe vectors

open access: yesJournal of High Energy Physics, 2018
We consider gl2 $$ \mathfrak{g}{\mathfrak{l}}_2 $$-invariant quantum integrable models solvable by the algebraic Bethe ansatz. We show that the form of on-shell Bethe vectors is preserved under certain twist transformations of the monodromy matrix.
S. Belliard, N. A. Slavnov
doaj   +1 more source

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