Results 61 to 70 of about 137,094 (294)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Kadomtsev–Petviashvili Hierarchy: Negative Times
Mathematics, 2021 The Kadomtsev–Petviashvili equation is known to be the leading term of a semi-infinite hierarchy of integrable equations with evolutions given by times with positive numbers. Here, we introduce new hierarchy directed to negative numbers of times.
Andrei K. Pogrebkov
doaj +1 more source
, 2010 Two hierarchies of nonlinear soliton equations are derived from a discrete spectral problem. It is shown that the hierarchies are completely integrable Hamiltonian systems.
HONG-QING ZHAO, YE-PENG SUN
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Negative flows of generalized KdV and mKdV hierarchies and their gauge-Miura transformations
Journal of High Energy Physics, 2023 The KdV hierarchy is a paradigmatic example of the rich mathematical structure underlying integrable systems and has far-reaching connections in several areas of theoretical physics.
Ysla F. Adans +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Journal of High Energy Physics, 2019 We construct N = 4 D 2 , 1 ; α $$ \mathcal{N}=4D\left(2,1;\ \alpha \right) $$ superconformal quantum mechanical system for any configuration of vectors forming a ∨-system.
Georgios Antoniou, Misha Feigin
doaj +1 more source
Gromov–Witten invariants and integrable hierarchies of topological type
, 2014 We outline two approaches to the construction of integrable hierarchies associated with the theory of Gromov--Witten invariants of smooth projective varieties.
Dubrovin, Boris +7 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Field analogue of the Ruijsenaars-Schneider model
Journal of High Energy Physics, 2022 We suggest a field extension of the classical elliptic Ruijsenaars-Schneider model. The model is defined in two different ways which lead to the same result.
A. Zabrodin, A. Zotov
doaj +1 more source