Results 41 to 50 of about 456 (259)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

On Cherednik and Nazarov-Sklyanin large N limit construction for integrable many-body systems with elliptic dependence on momenta

open access: yesJournal of High Energy Physics, 2021
The infinite number of particles limit in the dual to elliptic Ruijsenaars model (coordinate trigonometric degeneration of quantum double elliptic model) is proposed using the Nazarov-Sklyanin approach.
A. Grekov, A. Zotov
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Few Integrable Couplings of Some Integrable Systems and (2+1)-Dimensional Integrable Hierarchies

open access: yesAbstract and Applied Analysis, 2014
Two high-dimensional Lie algebras are presented for which four (1+1)-dimensional expanding integrable couplings of the D-AKNS hierarchy are obtained by using the Tu scheme; one of them is a united integrable coupling model of the D-AKNS hierarchy and the
Binlu Feng, Yufeng Zhang, Huanhe Dong
doaj   +1 more source

Kadomtsev–Petviashvili Hierarchy: Negative Times

open access: yesMathematics, 2021
The Kadomtsev–Petviashvili equation is known to be the leading term of a semi-infinite hierarchy of integrable equations with evolutions given by times with positive numbers. Here, we introduce new hierarchy directed to negative numbers of times.
Andrei K. Pogrebkov
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Negative flows of generalized KdV and mKdV hierarchies and their gauge-Miura transformations

open access: yesJournal of High Energy Physics, 2023
The KdV hierarchy is a paradigmatic example of the rich mathematical structure underlying integrable systems and has far-reaching connections in several areas of theoretical physics.
Ysla F. Adans   +4 more
doaj   +1 more source

Generalized W-algebras and integrable hierarchies [PDF]

open access: yesPhysics Letters B, 1992
9 ...
Burroughs, N.   +3 more
openaire   +4 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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