Results 91 to 100 of about 4,628 (266)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Global Kam-Theorem: Monodromy in Near-Integrable Perturbations of Spherical Pendulum

Journal of Mathematical and Fundamental Sciences, 2019
The KAM Theory for the persistence of Lagrangean invariant tori in nearly integrable Hamiltonian systems is lobalized to bundles of invariant tori. This leads to globally well-defined conjugations between near-integrable systems and their integrable ...
Henk W. Broer
doaj  

Pointwise Bounds for Joint Eigenfunctions of Quantum Completely Integrable Systems. [PDF]

Commun Math Phys, 2020
Galkowski J, Toth JA.
europepmc   +1 more source

Integrated Information Systems [PDF]

Yearbook of Medical Informatics, 1993
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Lectures on Classical Integrable Systems and Gauge Field Theories

Acta Polytechnica, 2008
In these lectures we consider Hitchin integrable systems and their relations with the self-duality equations and twisted super-symmetric Yang-Mills theory in four dimension.
M. Olshanetsky
doaj  

On dual regime in Yang-Baxter deformed O(2N) sigma models

Journal of High Energy Physics
In this paper, we explore a new class of integrable sigma models, which we refer to as the “dual regime” of Yang-Baxter (YB) deformed O(2N) sigma models. This dual regime manifests itself in the conformal perturbation approach.
Alexey Bychkov, Alexey Litvinov
doaj   +1 more source

N-Dimensional Lattice Integrable Systems and Their bi-Hamiltonian Structure on the Time Scale Using the R-Matrix Approach

Axioms
A time scale is a special measure chain that can unify continuous and discrete spaces, enabling the construction of integrable equations. In this paper, with the Lax operator generated by the displacement operator, N-dimensional lattice integrable ...
Yong Fang, Xue Sang, Manwai Yuen, Yong Zhang   +3 more
doaj   +1 more source

Direct linearization approach to discrete integrable systems associated with ℤ_𝒩 graded Lax pairs. [PDF]

Proc Math Phys Eng Sci, 2020
Fu W.
europepmc   +1 more source