Results 111 to 120 of about 14,181 (315)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 2006 The Hamiltonian equation provides us an alternate description of the basic physical laws of motion, which is used to be described by Newton's law.
Xuncheng Huang, Guizhang Tu
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Discretisation of Maxwell-Bloch dynamical systems [PDF]
, 2010 We investigate the smallest possible physically meaningful RMB model, which models propagation through a thin slab of resonant atomic material placed in a recirculating cavity, which has 2 degrees of freedom in the spatial distribution of the field . The
J. M. Arnold, Arnold, J.M.
core +1 more source
Algebro-Geometric Solutions for a Discrete Integrable Equation
Discrete Dynamics in Nature and Society, 2017 With the assistance of a Lie algebra whose element is a matrix, we introduce a discrete spectral problem. By means of discrete zero curvature equation, we obtain a discrete integrable hierarchy. According to decomposition of the discrete systems, the new
Mengshuang Tao, Huanhe Dong
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Formal Diagonalisation of Lax-Darboux Schemes
Моделирование и анализ информационных систем, 2015 We discuss the concept of Lax-Darboux scheme and illustrate it on well known examples associated with the Nonlinear Schro¨dinger (NLS) equation. We explore the Darboux links of the NLS hierarchy with the hierarchy of Heisenberg model, principal chiral ...
A. V. Mikhailov
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A class of equations with peakon and pulson solutions (with an Appendix by Harry Braden and John Byatt-Smith) [PDF]
, 2005 We consider a family of integro-differential equations depending upon a parameter b as well as a symmetric integral kernel g(x). When b=2 and g is the peakon kernel (i.e.
N W Hone +3 more
core +1 more source