Results 131 to 140 of about 9,007,112 (297)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Backlund transformations for the sl(2) Gaudin magnet [PDF]
, 2001 Elementary, one- and two-point, Backlund transformations are constructed for the generic case of the sl(2) Gaudin magnet. The spectrality property is used to construct these explicitly given, Poisson integrable maps which are time-discretizations of the ...
Kuznetsov, Vadim B. +2 more
core
A Global Kam-Theorem: Monodromy in Near-Integrable Perturbations of Spherical Pendulum
Journal of Mathematical and Fundamental Sciences, 2019 The KAM Theory for the persistence of Lagrangean invariant tori in nearly integrable Hamiltonian systems is lobalized to bundles of invariant tori. This leads to globally well-defined conjugations between near-integrable systems and their integrable ...
Henk W. Broer
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
AxiomsA time scale is a special measure chain that can unify continuous and discrete spaces, enabling the construction of integrable equations. In this paper, with the Lax operator generated by the displacement operator, N-dimensional lattice integrable ...
Yong Fang +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Lectures on Classical Integrable Systems and Gauge Field Theories
Acta Polytechnica, 2008 In these lectures we consider Hitchin integrable systems and their relations with the self-duality equations and twisted super-symmetric Yang-Mills theory in four dimension.
M. Olshanetsky
doaj
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source