Results 41 to 50 of about 4,628 (266)

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Simplifications of Lax pairs for differential–difference equations by gauge transformations and (doubly) modified integrable equations

open access: yesPartial Differential Equations in Applied Mathematics
Matrix differential–difference Lax pairs play an essential role in the theory of integrable nonlinear differential–difference equations. We present sufficient conditions which allow one to simplify such a Lax pair by matrix gauge transformations ...
Sergei Igonin
doaj   +1 more source

Deformation conjecture: deforming lower dimensional integrable systems to higher dimensional ones by using conservation laws

open access: yesJournal of High Energy Physics, 2023
Utilizing some conservation laws of (1+1)-dimensional integrable local evolution systems, it is conjectured that higher dimensional integrable equations may be regularly constructed by a deformation algorithm.
S. Y. Lou, Xia-zhi Hao, Man Jia
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Electric network and Hirota type 4-simplex maps

open access: yesJournal of High Energy Physics
Bazhanov-Stroganov (4-simplex) maps are set-theoretical solutions to the 4-simplex equation, namely the fourth member of the family of n-simplex equations, which are fundamental equations of mathematical physics.
S. Konstantinou-Rizos
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

2D Integrable systems, 4D Chern–Simons theory and affine Higgs bundles

open access: yesEuropean Physical Journal C: Particles and Fields, 2022
We compare the construction of 2D integrable models through two gauge field theories. The first one is the 4D Chern–Simons (4D-CS) theory proposed by Costello and Yamazaki.
A. Levin, M. Olshanetsky, A. Zotov
doaj   +1 more source

Variational integrators for almost-integrable systems [PDF]

open access: yesCelestial Mechanics and Dynamical Astronomy, 2008
14 pages, 4 figures.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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