Results 121 to 130 of about 5,324,251 (245)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The training of counselors to family in the race Degree in Psychology Eastern University

open access: yesSantiago, 2016
The present work is a synthesis of the investigative, theoretical and practical results of the family studies, in the Special Chair of Studies on Integral Formation of the Students at the Universidad de Oriente, in collaboration with several universities
Yolanda Mercerón-Figarola   +2 more
doaj  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Interdisciplinarity and its relationship with the European Middle Ages educational software

open access: yesRevista MENDIVE, 2005
This article presents the idea that the General Integral Professor should have a wide formative development, where he not only sees the phenomena from only one perspective in a determined science; instead he should see these phenomena as they manifest in
Ismary Fabe González   +1 more
doaj  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Reseña histórica de la Cátedra Martiana de la Facultad de Enfermería "Lidia Doce"

open access: yesRevista Habanera de Ciencias Médicas
La Extensión Universitaria de la Universidad de Ciencias Médicas de La Habana se ha redimensionado y dentro de su quehacer encontramos la atención a las Cátedras Martianas que constituyen un área de resultados claves de gran importancia en torno al ...
Miguel Ángel Velis Díaz
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Cooperative Education as central axis for the integral Formation in the cooperative sector

open access: yesCooperativismo y Desarrollo, 2013
The cooperative constitutes one of the most important sectors in the economy in any economic formation - social, its fundamental cell is the man's integral development who should be capable for, from a reflexive and creative position, to assume the ...
Iriadna Marín de León   +2 more
doaj  

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