Results 41 to 50 of about 207,867 (261)

Electrophysiological studies of Nephila clavata venom and toxin influence on hippocampal neuronal membranes after pretreatment with Aspergillus oryzae proteases

open access: yesБіологічні студії, 2020
Background. The use of Arthropodae toxins for electrophysiological experiments is very important, but experimental data in this regard are scarce. The aim of this study was to obtain experimental data about the influence of Nephila clavata spider venom ...
O. M. Klyuchko
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Robust Model Predictive Control of Heat Exchanger Network in the Presence of Fouling

open access: yesChemical Engineering Transactions, 2017
The aim of this paper is to present robust model predictive control (MPC) with integral action to optimize control performance of heat exchangers selected from a network, in the presence of fouling.
J. Oravec   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Nonlinear Receding-Horizon Control of Rigid Link Robot Manipulators

open access: yesInternational Journal of Advanced Robotic Systems, 2008
The approximate nonlinear receding-horizon control law is used to treat the trajectory tracking control problem of rigid link robot manipulators. The derived nonlinear predictive law uses a quadratic performance index of the predicted tracking error and ...
R. Hedjar, Boucher, P.
doaj  

A New Space-Time Theory Unravels the Origins of Classical Mechanics for the Dirac Equation

open access: yesQuantum Reports
The Feynman path integral plays a central role in quantum mechanics, linking classical action to propagators and relating quantum electrodynamics (QED) to Feynman diagrams.
Wei Wen
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Incremental least action principle in the framework of thermodynamics of irreversible processes

open access: yesPhysical Review Research, 2020
In this paper, an incremental least action principle is proposed using the framework of the thermodynamics of irreversible processes. First, we establish that an extensive thermodynamic potential defined over an infinitesimal volume satisfies a ...
V. Magnenet, J. Schmittbuhl
doaj   +1 more source

Multi-criteria Optimization of PD Controllers for Plants including Integral Action

open access: yes, 2018
A simple design method for robust PD controllers is presented for systems including integral action. The design method is based on a multi-criteria optimal control formulation, which is easily solved by a few lines of MATLAB code. Most criteria are based
Lennartson, Bengt,   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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