Results 41 to 50 of about 27,885 (268)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Finite Difference Scheme for Two-Dimensional Poisson Equation with the Multiple Integral Boundary Condition

open access: yesMathematics
This article investigates the numerical solution of the two-dimensional Poisson equation defined over a rectangular domain subject to a double integral nonlocal boundary condition.
Abdalaziz Bakhit   +2 more
doaj   +1 more source

Uniqueness of solutions of boundary value problems for Cauchy- Riemann equation with local and non- local boundary conditions

open access: yesپژوهش‌های ریاضی, 2021
In This paper, we consider two boundary value problems for non homogenuous  Cauchy- Riemann equation with  local and non-local boundary conditions separatly.In the first problem boundary condition is local and for proving uniqueness of solution, we show ...
Javad Ebadpur Golanbar   +2 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Boundary value problems with an integral constraint

open access: yesElectronic Journal of Differential Equations, 2015
We show the existence of solutions for a second-order ordinary differential equation coupled with a boundary-value condition and an integral condition.
Elisabetta M. Mangino, Eduardo Pascali
doaj  

Investigation of the spectrum for the Sturm-Liouville problem with one integral boundary condition

open access: yesNonlinear Analysis, 2010
In this paper, the Sturm–Liouville problem with one classical first type boundary condition and other nonlocal integral boundary conditions of two cases is investigated.
A. Skučaitė   +3 more
doaj   +1 more source

''New'' boundary conditions in integrable lattice models [PDF]

open access: yesProceedings of Non-perturbative Quantum Effects 2000 — PoS(tmr2000), 2000
4 pages, JHEP proceedings style, talk presented at the TMR conference ``Non-perturbative Quantum Effects 2000''
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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