Results 51 to 60 of about 27,885 (268)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Nonlocal problems for hyperbolic equations with degenerate integral conditions
Electronic Journal of Differential Equations, 2016 In this article, we consider a problem for hyperbolic equation with standard initial data and nonlocal condition. A distinct feature of this problem is that the nonlocal second kind integral condition degenerates and turns into a first kind.
Ludmila S. Pulkina
doaj
Mathematical Modelling and Analysis, 2012 In this work, we investigate a linear completely nonhomogeneous nonlocal multipoint problem for an m-order ordinary differential equation with generally variable nonsmooth coefficients satisfying some general properties such as p-integrability and ...
Kemal Ozen, Kamil Orucoglu
doaj +1 more source
On the solvability of parabolic and hyperbolicproblems with a boundary integral condition [PDF]
International Journal of Mathematics and Mathematical Sciences, 2002 We prove the existence, uniqueness, and the continuous dependence of a generalized solution upon the data of certain parabolic and hyperbolic equations with a boundary integral condition. The proof uses a functional analysis method based on a priori estimates established in nonclassical function spaces, and on the density of the range of the linear ...
openaire +3 more sources
Integrable boundary conditions for the Toda lattice [PDF]
Journal of Physics A: Mathematical and General, 1995 The problem of construction of the boundary conditions for the Toda lattice compatible with its higher symmetries is considered. It is demonstrated that this problem is reduced to finding of the differential constraints consistent with the ZS-AKNS hierarchy. A method of their construction is offered based on the Bäcklund transformations.
Adler, V. E., Habibullin, I. T.
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Arab Journal of Mathematical Sciences, 2019 A class of third order singularly perturbed convection diffusion type equations with integral boundary condition is considered. A numerical method based on a finite difference scheme on a Shishkin mesh is presented.
Velusamy Raja, Ayyadurai Tamilselvan
doaj +1 more source
Electromagnetic Scattering Analysis of SHDB Objects Using Surface Integral Equation Method
Photonics, 2020 A surface integral equation (SIE) method is applied in order to analyze electromagnetic scattering by bounded arbitrarily shaped three-dimensional objects with the SHDB boundary condition.
Beibei Kong +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source