Results 191 to 200 of about 21,307 (263)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Innovation by Design: Closing the Human-centered Design Skills Gap Among Front-line Nurses. [PDF]

J Nurs Adm
Holt JM, Talsma A, Taani MH, Avdeev I, Eckert CL, Mu Q, Ndakuya-Fitzgerald F, Jastrab J.   +7 more
europepmc   +1 more source

Twin Crystal Moiré Metasurfaces for Crossing Flat‐Band Transport

Advanced Functional Materials, EarlyView.
This study introduces twin crystal moiré metasurfaces, breaking in‐plane symmetry to enable reconfigurable acoustic wave manipulation. By adjusting the twin angle and interlayer twist angle, various combinations of hyperbolic, flat bands, and elliptic states can be synthesized in the system.
Shida Fan, Chenglin Han, Kuan He, Chadi Ellouzi, Yunlong Wang, Li‐Qun Chen, Jie Sun, Zhaodong Xu, Chen Shen, Tianzhi Yang   +9 more
wiley   +1 more source

Research on mechanical characteristics and key technology of integral intelligent lifting construction of large-span heavy steel box girder. [PDF]

PLoS One
Liu X, Li M, Geng Z, Zhu S, Li W, Liang B.   +5 more
europepmc   +1 more source

Bioinspired Mechanically Robust Organic–Inorganic Hybridized Bio‐Adhesives With up to 50% Inorganic Components by Bi‐Continuous Phase Engineering

Advanced Functional Materials, EarlyView.
A robust plant protein adhesive was prepared by fabricating a bi‐continuous organic–inorganic hybrid structure. Compared with traditional organic–inorganic hybrid adhesives, the addition amount of inorganic phase is increased from 0.2%–3.0% to 50%, and the strength and toughness are increased by 6 and 121 times, respectively.
Zheng Liu, Wenlong Luo, Xu Yang, Xin Zhang, Yuru Zhu, Jingchao Li, Jianzhang Li, Jing Luo, Zhezhe Zhou, Pingan Song, Qiang Gao   +10 more
wiley   +1 more source

Electrocapillary Modulated Interfacial Tension Amplifies Liquid Metal Transduction

Advanced Functional Materials, EarlyView.
This study presented an electrocapillary‐enhanced magnetohydrodynamic pumping strategy that harnesses the Lorentz force and interfacial tension modulation of liquid metal droplets to achieve amplified fluidic power. The system enabled low‐voltage, self‐oscillating fluidic transduction with enhanced pressure and flow generation, supporting compact ...
Saba Firouznia, Ciqun Xu, Michael D. Dickey, Jonathan Rossiter   +3 more
wiley   +1 more source

Dual molecular bridges at perovskite heterointerfaces for efficient inverted solar cells. [PDF]

Natl Sci Rev
Lian Q, Wang L, Wang G, Mi G, Li B, Smith JA, Caprioglio P, Kober-Czerny M, Wang D, Yin Q, Yang J, Li S, Liang X, Gong S, Li D, Hu H, Chen X, Guo X, Qiu L, Xu B, Li G, Ho-Baillie AWY, Zhang W, Luo G, Snaith HJ, Cheng C.   +25 more
europepmc   +1 more source

Hierarchical MXene‐Derived NTP/C Nanohybrids for Cryogenic Sodium‐Ion Batteries

Advanced Functional Materials, EarlyView.
A hierarchical MXene‐derived NaTi2(PO4)3/C nanohybrid enables efficient sodium‐ion storage down to −40°C by integrating fast ion–electron transport pathways with an ether‐based electrolyte. The system promotes dominant pseudocapacitive behavior and forms a robust inorganic‐rich SEI, collectively mitigating kinetic and interfacial limitations, thereby ...
M. Sai Bhargava Reddy, Mohammad Zaid, Sayan Das, Sooryadas Sudhakaran, Shampa Aich, Vilas G. Pol   +5 more
wiley   +1 more source

Bridging experiments and defects' mechanics: a data-driven toolbox for configurational force analysis. [PDF]

Eng Comput
Koko A, Abdelnour A, Becker TH, Marrow TJ.   +3 more
europepmc   +1 more source

Empirical aesthetics of bridges. [PDF]

PLoS One
Yang M, Damiano C, Gauvreau P, Walther DB.   +3 more
europepmc   +1 more source