Results 31 to 40 of about 13,785 (292)

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

Undergraduate students’ errors in integral calculus: A cognitive load theory perspective

open access: yesAlifmatika
This study aims to analyze students' errors in solving integral calculus problems based on Newmann's Error Analysis (NEA) and relate them to the Cognitive Load Theory (CLT) perspective. This study employs a descriptive quantitative approach, involving 74
Suharti Suharti, Puji Qur’ani Al Haq
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Fractional calculus of periodic distributions

open access: yes, 2011
Two approaches for defining fractional derivatives of periodic distributions are presented. The first is a distributional version of the Weyl fractional derivative in which a derivative of arbitrary order of a periodic distribution is defined via Fourier
Lamb, Wilson   +5 more
core   +1 more source

Integral Categories and Calculus Categories [PDF]

open access: yes, 2017
Differential categories are now a well-studied abstract setting for differentiation. However not much attention has been given to the process which is inverse to differentiation: integration. This thesis presents an analogous study of integral categories.
Lemay, Jean-Simon
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Generalized Quantum Integro-Differential Fractional Operator with Application of 2D-Shallow Water Equation in a Complex Domain

open access: yesAxioms, 2021
In this paper, we aim to generalize a fractional integro-differential operator in the open unit disk utilizing Jackson calculus (quantum calculus or q-calculus).
Rabha W. Ibrahim, Dumitru Baleanu
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Microlocal Analysis of Some Isospectral Deformations [PDF]

open access: yes, 1994
We study the microlocal structure of the examples of isospectral deformations of Riemannian manifolds given by D. DeTurck and C. Gordon in [DeT-G1]. The Schwartz kernel of the intertwining operators considered by them may be written as an oscillatory ...
Marhuenda, Francisco   +1 more
core  

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