Results 41 to 50 of about 13,785 (292)

Mengembangkan Perangkat Pembelajaran Kalkulus Integral Berbasis Model Pengajuan dan Pemecahan Masalah untuk Meningkatkan Kemampuan Berpikir Kreatif Mahasiswa

open access: yesJurnal Elemen, 2020
This study aims to develop learning set in the Integral calculus in the form of instructional design or study the concept of the volume of an Integral calculus rotating object that has a potential effect in improving student creative thinking skills ...
Edy Waluyo, Sri Supiyati, Muhammad Halqi
doaj   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Weddle's Inequality via Katugampola Fractional Integrals

open access: yesUniversal Journal of Mathematics and Applications
Integral inequalities represent an important and ongoing area of study in mathematical understanding. Due to their extensive use in science, fractional calculus approaches have been the subject of a great deal of research recently.
Jamal El-achky
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Integral de Riemann no Rn [PDF]

open access: yes, 2004
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Matemática.Neste trabalho, estudamos a Integral de Riemann, seus aspectos históricos e sua construção. Mostramos os teoremas de Darboux e Riemann
Leal Junior, Luiz Carlos
core  

Lorentzian quantum gravity via Pachner moves: one-loop evaluation

open access: yesJournal of High Energy Physics, 2023
Lorentzian quantum gravity is believed to cure the pathologies encountered in Euclidean quantum gravity, such as the conformal factor problem. We show that this is the case for the Lorentzian Regge path integral expanded around a flat background.
Johanna N. Borissova, Bianca Dittrich
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Problem solving in the teaching of single variable differential and integral calculus: Perspective of mathematics teachers

open access: yesUniciencia, 2018
There is a wide diversity of approaches to solving problems in the teaching of mathematics. In particular, the meaning of “problem solving” differs between theory and practice.
Cristian Alfaro-Carvajal   +1 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Calculus 2 [PDF]

open access: yes, 2020
Analysis is the field of mathematics that describes and analyzes quantitative changes, and the central methods are differential and integral calculus.
RICHARD, Serge
core  

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