Results 41 to 50 of about 194,925 (268)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Weddle's Inequality via Katugampola Fractional Integrals

Universal Journal of Mathematics and Applications
Integral inequalities represent an important and ongoing area of study in mathematical understanding. Due to their extensive use in science, fractional calculus approaches have been the subject of a great deal of research recently.
Jamal El-achky
doaj   +1 more source

Leitmann's direct method of optimization for absolute extrema of certain problems of the calculus of variations on time scales

, 2010
The fundamental problem of the calculus of variations on time scales concerns the minimization of a delta-integral over all trajectories satisfying given boundary conditions.
Agnieszka B. Malinowska, Almeida, Atici, Atici, Bartosiewicz, Bohner, Bohner, Bohner, Carlson, Carlson, Carlson, Carlson, Delfim F.M. Torres, Ferreira, Ferreira, Gouveia, Leitmann, Leitmann, Leitmann, Leitmann, Leitmann, Leitmann, Malinowska, Martins, Silva, Torres, Wagener, Zhan   +27 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Problem solving in the teaching of single variable differential and integral calculus: Perspective of mathematics teachers

Uniciencia, 2018
There is a wide diversity of approaches to solving problems in the teaching of mathematics. In particular, the meaning of “problem solving” differs between theory and practice.
Cristian Alfaro-Carvajal, Jennifer Fonseca-Castro   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PENGEMBANGAN MODUL PRAKTIKUM KALKULUS INTEGRAL BERBASIS APLIKASI WXMAXIMA TERHADAP PEMAHAMAN KONSEP MATEMATIS

Jurnal Pendidikan Matematika dan IPA, 2019
This study aims to determine whether there is difference and influence of Integral Calculus practical activity based on WxMaxima application on students concept comprehension ability.
Ivan Eldes Dafrita, Nurmaningsih Nurmaningsih   +1 more
doaj   +1 more source

A Differentiation Theory for It\^o's Calculus

, 2010
A peculiar feature of It\^o's calculus is that it is an integral calculus that gives no explicit derivative with a systematic differentiation theory counterpart, as in elementary calculus.
Bhattacharya R., Durrett R., Hassan Allouba, Royden H.   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Numerical Approximations and Fractional Calculus: Extending Boole’s Rule with Riemann–LiouvilleFractional Integral Inequalities

Fractal and Fractional
This paper develops integral inequalities for first-order differentiable convex functions within the framework of fractional calculus, extending Boole-type inequalities to this domain. An integral equality involving Riemann–Liouville fractional integrals
Abdul Mateen, Wali Haider, Asia Shehzadi, Hüseyin Budak, Bandar Bin-Mohsin   +4 more
doaj   +1 more source