Results 101 to 110 of about 222,134 (310)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Cyclic J integral using linear matching method

open access: yes, 2012
The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core  

Inverse problem of a hyperbolic equation with an integral overdetermination condition

open access: yesElectronic Journal of Differential Equations, 2016
In this article we study the inverse problem of a hyperbolic equation with an integral overdetermination condition. The existence, uniqueness and continuous dependence of the solution of the solution upon the data are established.
Taki-Eddine Oussaeif   +1 more
doaj  

To the Solution of Loaded Differential Equations with Nonlocal Conditions

open access: yesИзвестия Иркутского государственного университета: Серия "Математика"
We investigate a system of linear ordinary differential equations containing point and integral loadings with nonlocal boundary conditions. Boundary conditions include integral and point values of the unknown function. An essential feature of the problem
V.M. Abdullaev
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Solution to nonlocal problems of pseudohyperbolic equations

open access: yesElectronic Journal of Differential Equations, 2014
In this article considers a nonlocal problem with integral condition for a fourth-order pseudohyperbolic equation. Existence and uniqueness of a generalized solution are proved.
Ludmila S.A Pulkina
doaj  

Well-posedness of elliptic-parabolic differential problem with integral condition

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
In this paper, we study a class of nonlocal boundary value problems for elliptic-parabolic equations subject to integral-type conditions. Such problems naturally emerge in various physical and engineering contexts, including diffusion processes in ...
O. Gercek
doaj   +1 more source

The radial integration boundary integral and integro-differential equation methods for numerical solution of problems with variable coefficients

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The boundary element method (BEM) has become a powerful method for the numerical solution of boundary-value problems (BVPs), due to its ability (at least ...
Al-Jawary, Majeed
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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