Results 101 to 110 of about 1,754,523 (282)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Solvability of a nonlocal problem for a hyperbolic equation with integral conditions

open access: yesElectronic Journal of Differential Equations, 2017
We study a nonlocal problem with integral conditions for a hyperbolic equation two independent variables. By introducing additional functional parameters, we investigated the solvability and construction of approximate solutions.
Anar T. Assanova
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A nonlocal mixed semilinear problem for second-order hyperbolic equations

open access: yesElectronic Journal of Differential Equations, 2003
In this work we study a nonlinear hyperbolic one-dimensional problem with a nonlocal condition. We establish a blow up result for large initial data and a decay result for small initial data.
Said Mesloub, Salim A. Messaoudi
doaj  

极大奇异积分算子的RBLO估计(A RBLO estimate for maximal singular integral operator)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2011
Let μ be a positive Radon measure and satisfy a growth condition on Rd. Considering maximal Calderón-Zygmund singular integral operator whose kernel is k(x, y).
QUANYu-xia(全玉霞)   +2 more
doaj   +1 more source

A boundary problem with integral gluing condition for a parabolic-hyperbolic equation involving the Caputo fractional derivative

open access: yes, 2013
In the present work we investigate the Tricomi problem with integral gluing condition for parabolic-hyperbolic equation with the Caputo fractional order derivative.
Akhatov, Jasurjon S.   +1 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

olution to a semilinear pseudoparabolic problem with integral conditions

open access: yesElectronic Journal of Differential Equations, 2006
In this article, we use the Rothe time-discretization method to prove the well-posedness of a mixed problem with integral conditions for a third order semilinear pseudoparabolic equation.
Abdelfatah Bouziani, Nabil Merazga
doaj  

POINT-WISE CONVERGENCE OF INVERSE INTEGRAL WAVELET TRANSFORM UNDER DINI CONDITION

open access: yesНаука и техника, 2006
The paper develops a formula for an inversion of the integral wavelet transform in the space of square-summed-up functions and reveals a point-wise convergence of the inverse wavelet transform under Dini condition.
O. V. Doubrovina
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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