Results 91 to 100 of about 1,754,523 (282)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Solution to nonlocal problems of pseudohyperbolic equations

open access: yesElectronic Journal of Differential Equations, 2014
In this article considers a nonlocal problem with integral condition for a fourth-order pseudohyperbolic equation. Existence and uniqueness of a generalized solution are proved.
Ludmila S.A Pulkina
doaj  

Well-posedness of elliptic-parabolic differential problem with integral condition

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
In this paper, we study a class of nonlocal boundary value problems for elliptic-parabolic equations subject to integral-type conditions. Such problems naturally emerge in various physical and engineering contexts, including diffusion processes in ...
O. Gercek
doaj   +1 more source

Spectrum Curves for Sturm–Liouville Problem with Integral Boundary Condition

open access: yesMathematical Modelling and Analysis, 2015
We consider Sturm–Liouville problem with one integral type nonlocal boundary condition depending on three parameters γ (multiplier in nonlocal condition), ξ1, ξ2 ([ξ1, ξ2] is a domain of integration).
Agnė Skučaitė, Artūras Štikonas
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Higher order boundary value problems at resonance on an unbounded interval

open access: yesElectronic Journal of Differential Equations, 2016
The aim of this paper is the solvability of a class of higher order differential equations with initial conditions and an integral boundary condition on the half line.
Assia Frioui   +2 more
doaj  

Finite Difference Scheme for Two-Dimensional Poisson Equation with the Multiple Integral Boundary Condition

open access: yesMathematics
This article investigates the numerical solution of the two-dimensional Poisson equation defined over a rectangular domain subject to a double integral nonlocal boundary condition.
Abdalaziz Bakhit   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Investigation of the Sturm–Liouville problems with integral boundary condition

open access: yesLietuvos Matematikos Rinkinys, 2011
This paper presents some new results on the spectrum of a complex plane for the second order Finite-Difference Scheme with one integral type nonlocal boundary condition (NBC).
Agnė Skučaitė, Artūras Štikonas
doaj   +1 more source

Home - About - Disclaimer - Privacy