Results 71 to 80 of about 222,134 (310)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Stability analysis for boundary value problems with generalized nonlocal condition via Hilfer–Katugampola fractional derivative

Advances in Difference Equations, 2020
In this research, we present the stability analysis of a fractional differential equation of a generalized Liouville–Caputo-type (Katugampola) via the Hilfer fractional derivative with a nonlocal integral boundary condition.
Idris Ahmed, Poom Kumam, Fahd Jarad, Piyachat Borisut, Kanokwan Sitthithakerngkiet, Alhassan Ibrahim   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

On the integration of the diffusion equation with boundary conditions. [PDF]

Transactions of the American Mathematical Society, 1961
the initial-value problem is shown to have a unique positivity preserving solution; here an1= aiini, bn = bini (the ni being components of the outer normal to A), oa, r > 0, and a2 +r2 = 1. Solutions in the form of strongly continuous semi-groups of positive operators (see [4]) are obtained in the Lp spaces over A with weight factor e, 1 ?_ _ 2.
openaire   +2 more sources

Perturbed conformal field theory, nonlinear integral equations and spectral problems [PDF]

, 2000
This thesis is concerned with various aspects of perturbed conformal field theory and the methods used to calculate finite-size effects of integrable quantum field theories.
Dunning, Tania Clare, Tania Clare Dunning, Dunning, T.C.   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Integrated Conditional Estimation-Optimization

Operations Research
Many real-world optimization problems involve uncertain parameters with probability distributions that can be estimated using contextual feature information. In contrast to the standard approach of first estimating the distribution of uncertain parameters and then optimizing the objective based on the estimation, we propose an integrated conditional ...
Meng Qi, Paul Grigas, Zuo-Jun (Max) Shen
openaire   +2 more sources

Microlocal Analysis of Some Isospectral Deformations [PDF]

, 1994
We study the microlocal structure of the examples of isospectral deformations of Riemannian manifolds given by D. DeTurck and C. Gordon in [DeT-G1]. The Schwartz kernel of the intertwining operators considered by them may be written as an oscillatory ...
Marhuenda, Francisco, Marhuenda Hurtado, Francisco   +1 more
core  

Positive nondecreasing solutions for a multi-term fractional-order functional differential equation with integral conditions

Electronic Journal of Differential Equations, 2011
In this article, we prove the existence of positive nondecreasing solutions for a multi-term fractional-order functional differential equations. We consider Cauchy boundary problems with: nonlocal conditions, two-point boundary conditions, integral ...
Ahmed M. A. El-Sayed, Ebtisam O. Bin-Taher   +1 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source