Results 61 to 70 of about 199,409 (217)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Investigation of the Sturm–Liouville problems with integral boundary condition
Lietuvos Matematikos Rinkinys, 2011 This paper presents some new results on the spectrum of a complex plane for the second order Finite-Difference Scheme with one integral type nonlocal boundary condition (NBC).
Agnė Skučaitė, Artūras Štikonas
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Solvability of a nonlocal problem for a hyperbolic equation with integral conditions
Electronic Journal of Differential Equations, 2017 We study a nonlocal problem with integral conditions for a hyperbolic equation two independent variables. By introducing additional functional parameters, we investigated the solvability and construction of approximate solutions.
Anar T. Assanova
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
A nonlocal mixed semilinear problem for second-order hyperbolic equations
Electronic Journal of Differential Equations, 2003 In this work we study a nonlinear hyperbolic one-dimensional problem with a nonlocal condition. We establish a blow up result for large initial data and a decay result for small initial data.
Said Mesloub, Salim A. Messaoudi
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极大奇异积分算子的RBLO估计(A RBLO estimate for maximal singular integral operator)
Zhejiang Daxue xuebao. Lixue ban, 2011 Let μ be a positive Radon measure and satisfy a growth condition on Rd. Considering maximal Calderón-Zygmund singular integral operator whose kernel is k(x, y).
QUANYu-xia(全玉霞) +2 more
doaj +1 more source
POINT-WISE CONVERGENCE OF INVERSE INTEGRAL WAVELET TRANSFORM UNDER DINI CONDITION
Наука и техника, 2006 The paper develops a formula for an inversion of the integral wavelet transform in the space of square-summed-up functions and reveals a point-wise convergence of the inverse wavelet transform under Dini condition.
O. V. Doubrovina
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
olution to a semilinear pseudoparabolic problem with integral conditions
Electronic Journal of Differential Equations, 2006 In this article, we use the Rothe time-discretization method to prove the well-posedness of a mixed problem with integral conditions for a third order semilinear pseudoparabolic equation.
Abdelfatah Bouziani, Nabil Merazga
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