Results 121 to 130 of about 4,987,876 (357)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Solution to nonlocal problems of pseudohyperbolic equations

open access: yesElectronic Journal of Differential Equations, 2014
In this article considers a nonlocal problem with integral condition for a fourth-order pseudohyperbolic equation. Existence and uniqueness of a generalized solution are proved.
Ludmila S.A Pulkina
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Higher order boundary value problems at resonance on an unbounded interval

open access: yesElectronic Journal of Differential Equations, 2016
The aim of this paper is the solvability of a class of higher order differential equations with initial conditions and an integral boundary condition on the half line.
Assia Frioui   +2 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Nontrivial Solution of Fractional Differential System Involving Riemann-Stieltjes Integral Condition

open access: yesAbstract and Applied Analysis, 2012
We study the existence and uniqueness of nontrivial solutions for a class of fractional differential system involving the Riemann-Stieltjes integral condition, by using the Leray-Schauder nonlinear alternative and the Banach contraction mapping principle,
Ge-Feng Yang
doaj   +1 more source

Condition number estimates for combined potential boundary integral operators in acoustic scattering [PDF]

open access: bronze, 2009
Simon N. Chandler‐Wilde   +3 more
openalex   +1 more source

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