Results 31 to 40 of about 142,767 (307)

Consensus Standards and Recommendations for Developmental and Cognitive Surveillance, Screening, and Evaluation in Sickle Cell Disease: Executive Summary From the National Alliance of Sickle Cell Centers Neurocognitive Workgroup

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz, Donna Murdaugh, Andrew M. Heitzer, Jennifer N. Longoria, Wendy Santos‐Modesitt, Arianna Martin, Judy Cavazos, Jeff Schatz, Catherine R. Hoyt, Alison King, Eboni I. Lance, Steven Hardy, Marsha Treadwell   +12 more
wiley   +1 more source

Asymptotic Behavior of Solutions to Delayed Nonlinear Integral Equations Influenced by Growth Rates and Time Delays

Mathematics
This study examines partial differential equation models with delay on both unbounded and bounded domains. The mathematical model is reformulated as a system of nonlinear integral equations.
Khalaf M. Alanazi
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On the Abscissa of Convergence of Laplace–Stieltjes Integrals in the Euclidean Real Vector Space ${\mathbb{R}}^p$

Axioms
New estimates for the convergence abscissas of the multiple Laplace–Stieltjes integral are obtained. There is described the relationship between the integrand function, the Lebesgue–Stieltjes measure, and the abscissa of convergence of the multiple ...
Andriy Bandura, Oleh Skaskiv, Olha Zadorozhna   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Marcinkiewicz integrals along subvarieties on product domains

International Journal of Mathematics and Mathematical Sciences, 2004
We study the Lp mapping properties of a class of Marcinkiewicz integral operators on product domains with rough kernels supported by subvarieties.
Ahmad Al-Salman
doaj   +1 more source

Estimates for Generalized Parabolic Marcinkiewicz Integrals with Rough Kernels on Product Domains

Axioms, 2023
We prove Lp estimates of a class of generalized Marcinkiewicz integral operators with mixed homogeneity on product domains. By using these estimates along with an extrapolation argument, we obtain the boundedness of our operators under very weak ...
Mohammed Ali, Hussain Al-Qassem
doaj   +1 more source

Integral Closures of Noetherian Integral Domains as Intersections [PDF]

Proceedings of the American Mathematical Society, 1995
Let \(A\) be a noetherian integral domain, \(\overline A\) its integral closure, and let \({\mathcal G}\) be the set of prime ideals \(P\) of \(A\) with height\((P) \leq 1\). The author provides three equivalent conditions for the equality \(\overline A = \bigcap \overline A_P\), \(P \in {\mathcal G}\). For instance, equality holds iff \(\bigcap A_P\),
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source