Results 81 to 90 of about 679,276 (278)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Accurate Nonstandard Path Integral Models for Arbitrary Dielectric Boundaries in 2-D NS-FDTD Domains

Sensors
An efficient path integral (PI) model for the accurate analysis of curved dielectric structures on coarse grids via the two-dimensional nonstandard finite-difference time-domain (NS-FDTD) technique is introduced in this paper.
Tadao Ohtani, Yasushi Kanai, Nikolaos V. Kantartzis   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Essential Gronwall Inequality Demands the $\left(\rho,\varphi \right) -$Fractional Operator with Applications in Economic Studies

Universal Journal of Mathematics and Applications
Gronwall's inequalities are important in the study of differential equations and integral inequalities. Gronwall inequalities are a valuable mathematical technique with several applications.
Rabha Ibrahim, Zoubir Dahmani, Mohamed Bezzıou   +2 more
doaj   +1 more source

Integral Closures of Noetherian Integral Domains as Intersections [PDF]

Proceedings of the American Mathematical Society, 1995
Let \(A\) be a noetherian integral domain, \(\overline A\) its integral closure, and let \({\mathcal G}\) be the set of prime ideals \(P\) of \(A\) with height\((P) \leq 1\). The author provides three equivalent conditions for the equality \(\overline A = \bigcap \overline A_P\), \(P \in {\mathcal G}\). For instance, equality holds iff \(\bigcap A_P\),
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

NECESSARY AND SUFFICIENT CONDITIONS OF (α, β)-ACCESSIBILITY OF DOMAIN IN NONSMOOTH CASE

Проблемы анализа, 2015
In [1], [2] (α, β)-accessible domains in C were defined and investigated, and the criterion of (α, β)-accessibility in a smooth case was obtained. (α, β)-accessible domains are starlike, γ-accessible (γ = min{α, β}), and satisfy the so-called “cone ...
K. F. Amozova
doaj   +1 more source

Factorization in integral domains, III

Journal of Pure and Applied Algebra, 1999
Les auteurs continuent l'étude des propriétés arithmétiques des anneaux intègres [\textit{D. D. Anderson}, \textit{D. F. Anderson} and \textit{M. Zafrullah}, J. Pure Appl. Algebra 69, No. 1, 1-19 (1990; Zbl 0727.13007) and J. Algebra 152, No. 1, 78-93 (1992; Zbl 0776.13001)].
Anderson, David F., El Abidine, Driss Nour   +1 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source