Results 151 to 160 of about 5,360,556 (378)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Some new nonlinear integral inequalities and their applications in the qualitative analysis of differential equations

open access: yesJournal of Inequalities and Applications, 2011
In this paper, some new nonlinear integral inequalities are established, which provide a handy tool for analyzing the global existence and boundedness of solutions of differential and integral equations.
Zheng Bin, Feng Qinghua
doaj  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Numerical solution of singular integro-differential Prandtl equation by the method of orthogonal polynomials

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2019
The paper is constructed and proved computational scheme for a solution of singular Prandtl of integro-differential  equations with singular integral over the interval of the real axis, understood in the sense of the Cauchy principal value.
Galina A. Rasolko
doaj  

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