Results 61 to 70 of about 181,927 (288)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Electronic Journal of Differential Equations, 2018 In this article we study applications of integral transforms composition method (ITCM) for obtaining transmutations via integral transforms. It is possible to derive wide range of transmutation operators by this method.
Ahmed Fitouhi +3 more
doaj
Second order elliptic partial differential equations driven by Lévy white noise
Modern Stochastics: Theory and Applications, 2021 This paper deals with linear stochastic partial differential equations with variable coefficients driven by Lévy white noise. First, an existence theorem for integral transforms of Lévy white noise is derived and the existence of generalized and mild ...
David Berger, Farid Mohamed
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A note on integral transforms and differential equations [PDF]
, 2012 In this work a new integral transform, namely Sumudu transform was applied to solve linear ordinary differential equations with constant coefficients with convolution terms.
Eltayeb, Hassan +2 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
General convolutions of integral transforms and their application to ode and PDE problems
Mathematical Modelling and Analysis, 2006 The present research is devoted to some polyconvolutions generated by various integral transforms. For example, we study convolutions of the Hankel transform with the following factorization properties: where Hv[f] (x) is the Hankel transform.
L. E. Britvina
doaj +1 more source
New homotopy analysis transform method for solving multidimensional fractional diffusion equations
Arab Journal of Basic and Applied Sciences, 2020 In this paper, we introduce a new semi-analytical method called the homotopy analysis Shehu transform method (HASTM) for solving multidimensional fractional diffusion equations.
Shehu Maitama, Weidong Zhao
doaj +1 more source
, 2022 Abstract The major objective of this paper is to propose a novel double Laplace – ARA transforms (DL-ARAT). We employ this transform to prove the convolution, existence and other relevant theorems as well as derivatives properties. Subsequently, this method is applied to solve some illustrative integral- differential equations.
Abdelilah Sedeeg +4 more
openaire +1 more source