Results 121 to 130 of about 527,109 (283)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Boundedness of several operators on weighted Herz spaces
Journal of Function Spaces and Applications, 2009 We consider the boundedness of singular integral operators and fractional integral operators on weighted Herz spaces. For this purpose we introduce generalized Herz space. Our results are the best possible.
Yasuo Komori, Katsuo Matsuoka
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Analogue Sochocky formulae for integral operators with additional logarithmic singularity
Журнал Белорусского государственного университета: Математика, информатика, 2018 In this paper we prove the limit formulas for singular integrals of the form. Limit values of such integrals are expressed in terms of singular integral operators and also integral operators.
Vitold V. Kashevski
doaj
Morrey Spaces for Nonhomogeneous Metric Measure Spaces
Abstract and Applied Analysis, 2013 The authors give a definition of Morrey spaces for nonhomogeneous metric measure spaces and investigate the boundedness of some classical operators including maximal operator, fractional integral operator, and Marcinkiewicz integral operators.
Cao Yonghui, Zhou Jiang
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Note on Generalized Fractional Integral Operators on Generalized Morrey Spaces
Boundary Value Problems, 2009 We show some inequalities for generalized fractional integral operators on generalized Morrey spaces. We also show the boundedness property of the generalized fractional integral operators on the predual of the generalized Morrey spaces.
Yoshihiro Sawano +2 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Hiperbolic singular integral operators
Revista Matemática Iberoamericana, 1995 We define a class of integral operators which are singular relative to the hyperbolic metric on simply connected domains of the plane. We study the necessary and sufficient conditions for such operators to be bounded on L^2 of the upper half plane ...
openaire +3 more sources