Results 101 to 110 of about 20,934 (266)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Convexity and Spirallikeness Conditions for Two New General Integral Operators
Journal of Mathematics, 2013 We define two new general integral operators for certain analytic functions in the unit disc and give some sufficient conditions for these integral operators on some subclasses of analytic functions.
H. Özlem Güney, Serap Bulut
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Starlike integral operators [PDF]
Pacific Journal of Mathematics, 1978 Miller, Sanford S. +2 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Analogue Sochocky formulae for integral operators with additional logarithmic singularity
Журнал Белорусского государственного университета: Математика, информатика, 2018 In this paper we prove the limit formulas for singular integrals of the form. Limit values of such integrals are expressed in terms of singular integral operators and also integral operators.
Vitold V. Kashevski
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COMMUTATORS OF SINGULAR INTEGRAL OPERATORS
Proceedings of the National Academy of Sciences, 1965 where x, y are points in n-dimensional Euclidean space R" and k(x) is a homogeneous function of degree -n with mean value zero on xl = 1, and let B(f) = b(x)f(x). It is well known (see ref. 1) that if k anid b are sufficiently smooth and b is bounded, then (AB BA)(0/0ax) and (0/ax) (AB BA) are bounded operators in Lp ...
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Boundedness of several operators on weighted Herz spaces
Journal of Function Spaces and Applications, 2009 We consider the boundedness of singular integral operators and fractional integral operators on weighted Herz spaces. For this purpose we introduce generalized Herz space. Our results are the best possible.
Yasuo Komori, Katsuo Matsuoka
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source