Modeling third waves of Covid-19 spread with piecewise differential and integral operators: Turkey, Spain and Czechia [PDF]
Atangana A, İğret Araz S.
europepmc +2 more sources
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Lipschitz Estimates for One-Sided Cohen’s Commutators on Weighted One-Sided Triebel-Lizorkin Spaces
We introduce one-sided Cohen’s commutators of singular integral operators and fractional integral operators, respectively. Using the extrapolation of one-sided weights, we establish the boundedness of these operators from weighted Lebesgue spaces to ...
Xiao Jin Zhang, Xian Ming Hou
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
In this article, we give the boundedness conditions in terms of Zygmund-type integral inequalities for oscillatory integral operators and fractional oscillatory integral operators on the vanishing generalized weighted Morrey spaces.
Bilal Çekiç +1 more
doaj +1 more source
On positive solutions of a system of equations generated by Hadamard fractional operators
This paper is devoted to studying some systems of quadratic differential and integral equations with Hadamard-type fractional order integral operators.
Amira M. Abdalla +2 more
doaj +1 more source
Diagonalization of Abel’s Integral Operator [PDF]
The author provides an explicit diagonalization of Abel's integral operator \(A\), given by \((Af) (x) =\) \(\int^ \infty_ x (y^ 2 - x^ 2)^{-1/2} f(y)dy\). This diagonalization has also been applied to stellar wind tomography, and apparently provides a quick diagonalization of \(A\).
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

