Correction: A micro-CT-integrated 3D simulation framework reveals fluid transport mechanisms and void dynamics in root canal fillings. [PDF]
Raoof A +4 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
There are thirty one-parameter Laplace-type integral transforms, however, two-parameter Laplace-type integral transforms are few. Hence, the objective in the paper is to introduce and apply a new two-parameter Laplace-type integral transform, called the
E. E. Iyeme +3 more
doaj
Three-dimensional dynamic response of infinite plate resting on multilayered orthotropic foundation under moving loads. [PDF]
Zhang CL, Cao M, Hong L, Qi YF.
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Stability analysis and numerical simulation of nonlocal extended epidemic models using positivity-preserving scheme. [PDF]
Yousuf M, Alshakhoury N.
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Duality of Shehu transform with other well known transforms and application to fractional order differential equations. [PDF]
Mlaiki N +4 more
europepmc +1 more source
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
Fundamental Solutions to Fractional Heat Conduction in Two Joint Half-Lines Under Conditions of Nonperfect Thermal Contact. [PDF]
Povstenko Y +3 more
europepmc +1 more source

