Results 61 to 70 of about 1,268,130 (291)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Integral transforms for engineers
, 1999 Integral transform methods provide effective ways to solve a variety of problems arising in the engineering, optical, and physical sciences. Suitable as a self-study for practicing engineers and applied mathematicians and as a textbook in graduate-level ...
Andrews, Larry C. +1 more
core
Solutions of certain initial-boundary value problems via a new extended Laplace transform
Nonlinear EngineeringIn this article, we present a novel extended exponential kernel Laplace-type integral transform. The Laplace, natural, and Sumudu transforms are all included in the suggested transform.
Almalki Yahya +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Lie Group Symmetries as Integral Transforms of Fundamental Solutions [PDF]
We obtain fundamental solutions for PDEs of the form ut = x uxx +f(x)ux ??xru by showing that if the symmetry group of the PDE is nontrivial, it contains a standard integral transform of the fundamental solution. We show that in this case, the problem of
Mark Craddock, Kelly A Lennox
core
Global behavior of integral transforms
Journal of Inequalities and Applications, 2006 We obtain global estimates for various integral transforms of positive differentiable functions that satisfy inequalities of the type , for .
Vindas Jasson, Estrada Ricardo
doaj
International Journal of Mathematics and Mathematical Sciences, 1988 A formula of inversion is established for an integral transform whose kernel is the Bessel function Ju(kr) where r varies over the finite interval (0,a) and the order u is taken to be the eigenvalue parameter.
D. Naylor
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Xấp xỉ hàm số bằng phép biến đổi tích phân mờ với phép toán nhân
Tạp chí Khoa học Đại học Cần ThơTrong bài báo này, một loại phép biến đổi tích phân mờ được xây dựng trên cơ sở phép toán nhân trong tập lưới dư thứ tự đầy đủ đã được giới thiệu. Một số tính chất cơ bản của phép biến đổi này được khảo sát.
Bùi Quốc Việc, Lâm Hoàng Chương
doaj +1 more source