Results 71 to 80 of about 1,268,130 (291)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2007 In the present article the authors introduce several new integral transforms including the L-4-transform and the P-4-transform as generalizations of the classical Laplace transform and the classical Stieltjes transform, respectively. It is shown that the
DERNEK, AYŞE NEŞE
core +1 more source
Axisymmetric solutions to Einstein field equations via integral transforms. [PDF]
Heliyon, 2023 Batic D, Debru NB, Nowakowski M.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
MULTIPLE FOURIER SERIES AND FOURIER INTEGRALS WITH NON-SEPARABLE VARIABLES
Известия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020 Background. Integral transforms for functions of several variables are an actively developing area of mathematical analysis. Numerous applications in integral transforms method for solving equations of mathematical physics, in signal processing of ...
O. E. Yaremko +2 more
doaj +1 more source
The alchemical integral transform revisited
The Journal of Chemical PhysicsWe recently introduced the Alchemical Integral Transform (AIT), enabling the prediction of energy differences, and guessed an ansatz to parameterize space r in some alchemical change λ. Here, we present a rigorous derivation of AIT’s kernel K and discuss the parameterization r(λ) in n dimensions, i.e., necessary conditions, mathematical freedoms, and ...
Simon León Krug +1 more
openaire +3 more sources
Efficient estimation of propagator anisotropy and non-Gaussianity in multishell diffusion MRI with micro-structure adaptive convolution kernels and dual Fourier integral transforms. [PDF]
Magn Reson Med, 2023 París G +3 more
europepmc +1 more source