Results 41 to 50 of about 3,608 (255)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Operational Solution of Non-Integer Ordinary and Evolution-Type Partial Differential Equations
Axioms, 2016 A method for the solution of linear differential equations (DE) of non-integer order and of partial differential equations (PDE) by means of inverse differential operators is proposed.
Konstantin V. Zhukovsky +1 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Generalized Fractional Integral Operators Involving Mittag-Leffler Function
Abstract and Applied Analysis, 2018 The aim of this paper is to study various properties of Mittag-Leffler (M-L) function. Here we establish two theorems which give the image of this M-L function under the generalized fractional integral operators involving Fox’s H-function as kernel ...
Hafte Amsalu, D. L. Suthar
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
On Symmetrical Sonin Kernels in Terms of Hypergeometric-Type Functions
MathematicsIn this paper, a new class of kernels of integral transforms of the Laplace convolution type that we named symmetrical Sonin kernels is introduced and investigated.
Yuri Luchko
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Communications in Advanced Mathematical SciencesIn this paper, a new generalization of the Laplace transform, called the $(k,\psi )$-generalized Laplace transform, which plays an important role in solving many problem models, is introduced and its special properties are given.
Emine Cengizhan +2 more
doaj +1 more source