Results 71 to 80 of about 167,020,740 (264)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Application of the generalized q-Mittag-Leffler function to fractional q-kinetic equations via q-Shehu transform

Kuwait Journal of Science
This paper investigates the properties and applications of q-Mittag-Leffler functions with five parameters within the framework of fractional q-kinetic equations.
Mulugeta Dawud Ali, D.L. Suthar
doaj   +1 more source

Heun Functions and Some of Their Applications in Physics

Advances in High Energy Physics, 2018
Most of the theoretical physics known today is described by using a small number of differential equations. For linear systems, different forms of the hypergeometric or the confluent hypergeometric equations often suffice to describe the system studied ...
M. Hortaçsu
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Operational Approach and Solutions of Hyperbolic Heat Conduction Equations

Axioms, 2016
We studied physical problems related to heat transport and the corresponding differential equations, which describe a wider range of physical processes. The operational method was employed to construct particular solutions for them.
Konstantin Zhukovsky
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The g-generalized Mittag-Leffler (p,s,k)-function

Alexandria Engineering Journal
The Mittag-Leffler (ML) function exists in the study of special functions. It may be used to solve a variety of fractional differential equations (FDEs) including fractional Laplace and fractional Poisson equations.
Umbreen Ayub, Madiha Shafiq, Amir Abbas, Umair Khan, Anuar Ishak, Y.S. Hamed, Homan Emadifar   +6 more
doaj   +1 more source

Mathematical modeling of hereditary elastically deformable body on the basis of structural models and fractional integrodifferentiation Riemann-Liouville apparatus

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2016
The standard one-dimensional generalized model of a viscoelastic body and some of its special cases-Voigt, Maxwell, Kelvin and Zener models are considered. Based on the V. Volterra hypothesis of hereditary elastically deformable solid body and the method
Eugeniy N Ogorodnikov, Vladimir P Radchenko, Luiza G Ungarova   +2 more
doaj   +1 more source

Convolution Theorem for (p,q)-Gamma Integral Transforms and Their Application to Some Special Functions

Symmetry
This article introduces (p,q)-analogs of the gamma integral operator and discusses their expansion to power functions, (p,q)-exponential functions, and (p,q)-trigonometric functions. Additionally, it validates other findings concerning (p,q)-analogs of the gamma integrals to unit step functions as well as first- and second-order (p,q)-differential ...
Shrideh Al-Omari, Wael Salameh, Hamzeh Zureigat   +2 more
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source