Results 111 to 120 of about 1,844 (267)

Long-range alternatives in Italian politics. [PDF]

open access: yes, 1954
Caption titleAt head of title: Economic development. Italy. Political/8. R. Zariski. January 28, 1954463"--handwritten on leaf [1].
Zariski, Raphael
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The New Myth: Frederic Spiegelberg and the Rise of a Whole Earth [PDF]

open access: yesIntegral Review, 2012
The present article provides, through the life and teachings of a little-known German scholar of religions named Frederic Spiegelberg (1897-1994), a novel account of some of the unique historical and intellectual developments that converged in the San ...
Ahmed M. Kabil
doaj  

Sociocultural genesis of Russia's vitality

open access: yesНаука. Культура. Общество, 2022
The Russian sociocultural potential of the vital force is considered in the context of the genesis of the concepts of the Slavophiles about its origins in those times when it was still mostly rural and peasant. The basic Slavophile’s, sociocultural ...
Vladimir I. Staroverov   +1 more
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Rescuing Maritain from His Reception History: A Reappraisal of William T. Cavanaugh’s Critique in Torture and Eucharist

open access: yesJournal of Moral Theology
The influential writings on church and state of philosopher Jacques Maritain, who died in 1973, possessed a mid-twentieth century hopefulness about a new birth of freedom and a lay-led Christian humanism.
Brian J. A. Boyd
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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