Results 101 to 110 of about 1,844 (267)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Adaptive Integration and Improper Integrals [PDF]

open access: yesMathematics of Computation, 1975
Let R be the class of all functions that are properly Riemann-integrable on [0, 1], and let IR be the class of all functions that are properly Riemann-integrable on [a, 1] for all a > 0 a > 0 and for which \[ lim a →
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Integral Text Linguistics as General Text Linguistics. Towards Coseriu’s Text Theory

open access: yesEIRP Proceedings, 2012
For over half a century, the text is one of the objects to which we had dedicated a lot of pages, bothwithin linguistics and the related scientific fields.
Delia Mărgărit
doaj  

Il curioso caso del Mahdi redivivo. Ricorrenza del Mahdismo dal colonialismo all'Isis [PDF]

open access: yes, 2018
The Mahdi is the eschatological figure of Islam who will rule over the world at the end of time after having rid humanity of evil. During the whole Islamic history, many rulers have claimed to be the long-awaited Mahdi, thus creating the conditions for ...
Arrigo, Giacomo Maria
core  

INTEGRATION OF PARTIALLY INTEGRABLE EQUATIONS [PDF]

open access: yesWaves and Stability in Continuous Media, 2006
12 p, WASCOM XIII (Acireale, 19-25 June 2005)
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Os camisas-verdes em Minas Gerais: o integralismo em São João del-Rei e o caso de Tancredo Neves = The green shirts in Minas Gerais: integralism in São João del-Rei and the Tancredo Neves’ case = Camisas verdes en Minas Gerais: integralismo en São João del-Rei y el caso de Tancredo Neves

open access: yesEstudos Ibero Americanos, 2021
O integralismo brasileiro pode ser considerado o maior movimento de expressão fascista latino-americano. No Brasil, através das bandeiras integralistas, alcançou uma expansão significativa em praticamente todos os estados.
Pimenta, Everton Fernando   +1 more
doaj  

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