Results 101 to 110 of about 707 (206)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
INTEGRALISME ISLAM DAN BUDAYA LOKAL Relevansi Nilai-Nilai Filosofis Budaya Lampung Bagi Pembangunan Daerah [PDF]
, 2017 This study reveals Integralism of Islam and Local Culture, which focused on the relevance of philosophical values of Lampung Culture for Pesawaran development.
Nurdin, A. Fauzie
core +1 more source
A evolução dos estudos sobre o integralismo = The evolution of studies about the Integralism
Estudos Ibero Americanos, 2010 Pretendo fazer neste artigo um resgate da produção acadêmica sobre o integralismo, desde a fundação do movimento, com a Ação Integralista Brasileira (AIB 1932-1937) e a rearticulação enquanto agremiação política, o Partido de Representação Popular (PRP
Oliveira, Rodrigo Santos de
doaj
The social bases of Integralism: Historiography and propositions
This paper is concerned with the reasons of part of the Brazilian middle classes for supporting integralism. It begins with an extensive bibliographic review of integralism to assess the documentary data available about the social base of the movement ...
Vannucchi, Marco Aurélio
core
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2015 O trabalho tem como proposta a análise do arcabouço doutrinário do Integralismo Lusitano, liderado por António Sardinha, e de seu desdobramento, o Nacional Sindicalismo.
Cazetta, Felipe Azevedo
core +1 more source