Results 101 to 110 of about 1,844 (267)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Adaptive Integration and Improper Integrals [PDF]
Let R be the class of all functions that are properly Riemann-integrable on [0, 1], and let IR be the class of all functions that are properly Riemann-integrable on [a, 1] for all a > 0 a > 0 and for which \[ lim a →
openaire +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Integral Text Linguistics as General Text Linguistics. Towards Coseriu’s Text Theory
For over half a century, the text is one of the objects to which we had dedicated a lot of pages, bothwithin linguistics and the related scientific fields.
Delia Mărgărit
doaj
Il curioso caso del Mahdi redivivo. Ricorrenza del Mahdismo dal colonialismo all'Isis [PDF]
The Mahdi is the eschatological figure of Islam who will rule over the world at the end of time after having rid humanity of evil. During the whole Islamic history, many rulers have claimed to be the long-awaited Mahdi, thus creating the conditions for ...
Arrigo, Giacomo Maria
core
INTEGRATION OF PARTIALLY INTEGRABLE EQUATIONS [PDF]
12 p, WASCOM XIII (Acireale, 19-25 June 2005)
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
O integralismo brasileiro pode ser considerado o maior movimento de expressão fascista latino-americano. No Brasil, através das bandeiras integralistas, alcançou uma expansão significativa em praticamente todos os estados.
Pimenta, Everton Fernando +1 more
doaj

