Results 81 to 90 of about 1,844 (267)

The War from Afghanistan (1979–1989) in the Memory of Participants from the Republic of Moldova. Official and Oral Speech [PDF]

open access: yes
This article presents the consequences caused by the war in Afghanistan (1979-1989) upon the participants from Republic of Moldova. A number of evidence are offered through biographies, interviews etc..
Ph.D. Ion XENOFONTOV
core   +1 more source

The Reality of the Refugee Crisis in Italy: A Look into the Lives of Illegitimate Refugees and the Unofficial Organizations That Support Them [PDF]

open access: yes, 2018
The words written on the United States of America’s famous Statue of Liberty, written by poet Emma Lazarus over a century ago: Give me your tired, your poor, your huddled masses yearning to breathe free The wretched refuse of your teeming shore ...
McQuirk, Cole
core   +2 more sources

Integrating the Integration

open access: yesJournal of Problem Based Learning in Higher Education, 2023
This paper provides a conceptual elaboration of the role of Problem-based Learning (PBL) in the integration of social sciences and humanities (SSH) with science, technology, engineering, and mathematics (STEM), and an analysis of the challenges this brings about.
Antonia Scholkmann   +2 more
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Christianity, Culture, and the Real: From Maritain’s Integral Humanism to a New Integralism?

open access: yesReligions
Jacques Maritain’s understanding of integral humanism influenced the relationship between Christianity and culture at the Second Vatican Council, yet soon afterward, Maritain recognised that in many instances it was misinterpreted, leading Catholics and ...
Mary McCaughey
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Segni dei tempi, sinodalità, "gender" [PDF]

open access: yes, 2019
My analysis on the category of signs of times (SoT) shows how it can help to explain a few aspects of synodality. I will explain how synodality and SoT support each other and why Synods should teach a correct judgment of SoT. It is a way to educate God's
Migliorini, Damiano
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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