Results 71 to 80 of about 225 (222)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
INTEGRATION OF PARTIALLY INTEGRABLE EQUATIONS [PDF]
Waves and Stability in Continuous Media, 2006 12 p, WASCOM XIII (Acireale, 19-25 June 2005)
openaire +2 more sources
Catholic fundamentalism: towards a discussion of the phenomenon and the application of the term [PDF]
Вестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философияThe article is devoted to the topic of catholic fundamentalism, which is not sufficiently highlighted in Russian church-historical science. It aims to update the discussion on the possibility of the religious phenomenon Catholic Fundamentalism, as well ...
Dmitriy Golovushkin
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Integral Text Linguistics as General Text Linguistics. Towards Coseriu’s Text Theory
EIRP Proceedings, 2012 For over half a century, the text is one of the objects to which we had dedicated a lot of pages, bothwithin linguistics and the related scientific fields.
Delia Mărgărit
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Pope Francis’s Proposition of Integral Ecology
Problemy Ekorozwoju, 2019 In spite of the fact that Pope Francis’s environmental message is not the first one to be formulated by the authorities of the Catholic Church, it is in this particular one that threads become visible which allow to see in it new, far-reaching analyses ...
Krzysztof Bochenek
doaj