Results 111 to 120 of about 528,990 (275)

On multiplicative conformable fractional integrals: theory and applications

open access: yesBoundary Value Problems
In this paper, we first introduce the multiplicative conformable left and right fractional integrals, followed by the derivation of key properties, such as integrability, boundedness, continuity, and the semi-group property, for the newly defined ...
Hüseyin Budak, Büşra Betül Ergün
doaj   +1 more source

Strongly tempered hyperspherical Hamiltonian spaces

open access: yesForum of Mathematics, Sigma
In this paper, we give a complete list of strongly tempered anomaly-free hyperspherical Hamiltonian spaces-those that are dual to symplectic vector spaces under the relative Langlands duality.
Zhengyu Mao, Chen Wan, Lei Zhang
doaj   +1 more source

Comparison of Different Approaches to Construct First Integrals for Ordinary Differential Equations

open access: yesAbstract and Applied Analysis, 2014
Different approaches to construct first integrals for ordinary differential equations and systems of ordinary differential equations are studied here. These approaches can be grouped into three categories: direct methods, Lagrangian or partial Lagrangian
Rehana Naz   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Framework for Non-Gaussian Functional Integrals with Applications

open access: yes, 2019
Functional integrals can be defined in terms of families of locally compact topological groups and their associated Banach-valued Haar integrals. The definition forgoes the goal of constructing a genuine measure on the domain of integration, but instead ...
LaChapelle, J.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Basso-Dixon formula and Calabi-Yau geometry

open access: yesJournal of High Energy Physics
We analyse the family of Calabi-Yau varieties attached to four-point fishnet integrals in two dimensions. We find that the Picard-Fuchs operators for fishnet integrals are exterior powers of the Picard-Fuchs operators for ladder integrals.
Claude Duhr   +4 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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