Results 171 to 180 of about 54,271 (286)

Identification of a nucleotide binding site in HIV-1 integrase

, 1998
Richard R. Drake, Nouri Neamati, Huixiao Hong, André A. Pilon, Prasanna Sunthankar, Steven D. Hume, G. W. A. Milne, Yves Pommier   +7 more
openalex   +1 more source

Molecular Organization in Site-Specific Recombination: The Catalytic Domain of Bacteriophage HP1 Integrase at 2.7 Å Resolution [PDF]

, 1997
Alison B. Hickman, Shani Waninger, John J. Scocca, Fred Dyda   +3 more
openalex   +1 more source

Inhibition of human immunodeficiency virus integrase by bis-catechols

, 1995
Robert L. LaFemina, Pia Graham, K LeGrow, J C Hastings, Abigail Wolfe, Steven D. Young, Emilio A. Emini, Daria J. Hazuda   +7 more
openalex   +1 more source

Human endogenous retrovirus K10 encodes a functional integrase [PDF]

, 1996
Yoshihiro Kitamura, T Ayukawa, Tetsuya Ishikawa, T. Kanda, K Yoshiike   +4 more
openalex   +1 more source

Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: a fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase–RNase H domain exhibits polymerase and RNase H activities [PDF]

, 2000
M.L. Wilhelm, Mansour Boutabout, François‐Xavier Wilhelm   +2 more
openalex   +2 more sources

Design, synthesis, molecular dynamics studies and biological evaluations of 4-hydroxy-5-pyrrolinone-3-carbohydrazides as HIV-1 integrase inhibitors

European Journal of Medicinal Chemistry Reports
Acquired immune deficiency syndrome (AIDS) diseases despite the efficacy of anti-HIV therapy, remain one of the human's most serious problems. Hence, the introduction of novel anti-HIV agents as first-line therapy is still required. HIV integrase lacking
Nafiseh Karimi, Amirreza Dowlati Beirami, Rouhollah Vahabpour Roudsari, Zahra Hajimahdi, Afshin Zarghi   +4 more
doaj  

Characterization of the long-terminal repeat single-strand tail-binding site of Moloney-MuLV integrase by crosslinking

Biological Research, 2008
Processing of viral DNA by retroviral integrase leaves a dinucleotide single-strand overhang in the unprocessed strand. Previous studies have stressed the importance of the 5' single-stranded (ss) tail in the integration process.
JORGE VERA, BEATRIZ VALENZUELA, MÓNICA J ROTH, ÓSCAR LEÓN   +3 more
doaj  

Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity

, 1995
Alan Engelman, Robert Craigie
openalex   +1 more source

Tn916 target DNA sequences bind the C-terminal domain of integrase protein with different affinities that correlate with transposon insertion frequency [PDF]

, 1995
Fengxia Lü, Glen Churchward
openalex   +1 more source

Point Mutations in the Integron Integrase IntI1 That Affect Recombination and/or Substrate Recognition [PDF]

, 1998
Annie Gravel, Nancy Messier, Paul H. Roy
openalex   +1 more source