Exploring the untapped potential of single‐cell and spatial omics in plant biology
New Phytologist, Volume 247, Issue 3, Page 1098-1116, August 2025.Summary Advances in single‐cell and spatial omics technologies have revolutionised biology by revealing the diverse molecular states of individual cells and their spatial organization within tissues. The field of plant biology has widely adopted single‐cell transcriptome and chromatin accessibility profiling and spatial transcriptomics, which extend ...
Tatsuya Nobori
wiley +1 more source
Molecular Organization in Site-Specific Recombination: The Catalytic Domain of Bacteriophage HP1 Integrase at 2.7 Å Resolution [PDF]
, 1997 Alison B. Hickman +3 more
openalex +1 more source
Diverging repeatomes in holoparasitic Hydnoraceae uncover a playground of genome evolution
New Phytologist, Volume 247, Issue 3, Page 1520-1537, August 2025.Summary The transition from an autotrophic to a heterotrophic lifestyle is associated with numerous genomic changes. These often involve large genomic alterations, potentially driven by repetitive DNAs. Despite their recognized role in shaping plant genomes, the contribution of repetitive DNAs to parasitic plant genome evolution remains largely ...
Woorin Kim +7 more
wiley +1 more source
Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity
, 1995 Alan Engelman, Robert Craigie
openalex +1 more source
Therapeutic Opportunities in Infectious Diseases: Highlights from the Society of Medicines Research Symposium, held on March 14th 2013 at the National Heart & Lung Institute, London, UK [PDF]
, 2013 Alderton, W K +3 more
core +1 more source
Inhibition of human immunodeficiency virus integrase by bis-catechols
, 1995 Robert L. LaFemina +7 more
openalex +1 more source
Tn916 target DNA sequences bind the C-terminal domain of integrase protein with different affinities that correlate with transposon insertion frequency [PDF]
, 1995 Fengxia Lü, Glen Churchward
openalex +1 more source
Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: a fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase–RNase H domain exhibits polymerase and RNase H activities [PDF]
, 2000 M.L. Wilhelm +2 more
openalex +2 more sources
Identification of a nucleotide binding site in HIV-1 integrase
, 1998 Richard R. Drake +7 more
openalex +1 more source
European Journal of Medicinal Chemistry ReportsAcquired immune deficiency syndrome (AIDS) diseases despite the efficacy of anti-HIV therapy, remain one of the human's most serious problems. Hence, the introduction of novel anti-HIV agents as first-line therapy is still required. HIV integrase lacking
Nafiseh Karimi +4 more
doaj