We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Reducing selection bias while maintaining precision through an integrated analysis: 2-year longitudinal analysis of imaging outcomes in the SPondyloArthritis Caught Early cohort. [PDF]
de Bruin LJE +11 more
europepmc +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Distribution and characteristics of ceftiofur-resistant Escherichia coli throughout the broiler production chain in Korea. [PDF]
Lee JK, Moon BY, Lim SK, Lee YJ.
europepmc +1 more source
Review of: "Sustainable Agriculture: Aquaponics-Integrated Greenhouse Cultivation of Cantaloupe with Drip Irrigation System" [PDF]
Liliana Cifuentes
openalex +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Implementing and evaluating an integrated self-directed learning method for 1<sup>st</sup> phase medical graduate students: A novel interdisciplinary approach in anatomy, physiology, and biochemistry. [PDF]
Sahasrabuddhe A +4 more
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Making UV light visible by exciting polarization-gate phototransistor to achieve energy transfer into GaN-based blue emission. [PDF]
Chu C +7 more
europepmc +1 more source
Integrating the Integrated Stress Response
Harinath Bahudhanapati, Daniel J. Kass
openaire +2 more sources

