Results 191 to 200 of about 2,770,732 (298)

Working together to improve health and social care outcomes in Scotland

International Journal of Integrated Care, 2015
Kathleen Bessos
doaj   +1 more source

A parallel-legged insect-scale robot based on actuation-structure integrated origami mechanism. [PDF]

Microsyst Nanoeng
Zhu Q, Jiang T, Luo Z, Zhu Y, Huang G.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Principles and priorities for integrated tuberculosis screening and care: A modified Delphi consensus exercise. [PDF]

PLOS Glob Public Health
Calderwood CJ, Kunor T, Coleman M, Marambire E, Khan U, Herrera R, Acaba J, Hussain Z, Bhattacharya D, Larsson L, Paredes JL, Paramo L, Chiluvane M, Nguyen TA, Hong HN, d'Elbée M, Kpokiri E, Vo LNQ, Wingfield T, Marais B, Bhargava M, Bernays S, Kranzer K.   +22 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Feasibility and acceptability of measurement-based care and integrated service delivery: a mixed methods research protocol for integrated youth services. [PDF]

BMJ Open
Henderson J, Chiodo D, Quinlan-Davidson M, Jackson-Best F, Barbic SP, Linklater R, Nyambi A, El Dahr Y, Dozet D, Varadi AL, Murcia D, Goldsmith R, Narajos A.   +12 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Nano-islands integrated evanescence-based lab-on-a-chip on silica-on-silicon and polydimethylsiloxane hybrid platform for detection of recombinant growth hormone [PDF]

, 2012
Jayan Ozhikandathil, Muthukumaran Packirisamy   +1 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Graphene-integrated microtube whispering-gallery mode resonators for polarization-sensitive optical modulation and photodetection. [PDF]

Light Sci Appl
Cai T, Zhang Z, Wu B, You J, Zheng Z, Wang Y, Bian C, Wang Y, Tian Y, Chi Y, Xiao Q, Ma M, Chen L, Liu J, Chen XZ, Song E, Cui J, Huang G, Mei Y.   +18 more
europepmc   +1 more source