Results 31 to 40 of about 816,242 (219)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

State‐space models and inference approaches for aquatic animal tracking with passive acoustic telemetry and biologging sensors

Methods in Ecology and Evolution
Passive acoustic telemetry systems are widely deployed to track animals in aquatic environments. However, investments in integrative methods of data analysis have remained comparatively limited, with current workflows typically considering individual ...
Edward Lavender, Andreas Scheidegger, Helen Moor, Carlo Albert   +3 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Male caregivers: a scoping review of impacts, needs, challenges, and best practices

Discover Health Systems
Although they play a crucial role in care trajectories and the quality of life of those they support, male caregivers (MCs) remain largely unrecognized, and the services available to assist them remain often insufficient or inadequate.
Bertine Sandra Akouamba, Sophie Audette-Chapdelaine, Ionela Gheorghiu, Hinatea Lai, Maggy Wassef, Adrian Mares, Walter Marcantoni   +6 more
doaj   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak, Rebecca Williamson‐Lewis, Michael O'Connor, Michael Palgon, Yu‐Ra Kim, Michael Schuckenbrock, Paula Edwards, Abraham Mendoza, Anthony Adams, Brian Arriaga‐Solis, Justin Parker, Harry Tinoco‐Giraldo, Jason King, C. Michael Fordis, Karen E. Effinger, Maria Monica Gramatges   +15 more
wiley   +1 more source

Assessing policy options for sustainable water use in India’s cereal production system

Environmental Research Letters, 2023
In India, the production of rice and wheat account for more than 80% of its total agricultural water use. As farming is highly dependent on water availability, rapidly receding water levels require urgent measures to manage withdrawals.
Vartika Singh, Miodrag Stevanović, Chandan Kumar Jha, Felicitas Beier, Ranjan Kumar Ghosh, Hermann Lotze-Campen, Alexander Popp   +6 more
doaj   +1 more source

Methodological Approaches to the Integrated Evaluation of Brand Strength Based on the System of Indicators and Modeling of Generalized Results of the Consumer Survey

Статистика и экономика, 2021
The article presents in detail the methodological approaches to calculating the integrated assessment of brand strength, as well as the results of testing the system of indicators and the mathematical model on the example of a comprehensive assessment of
O. A. Shikhova
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Economic damages from on-going climate change imply deeper near-term emission cuts

Environmental Research Letters, 2021
Pathways toward limiting global warming to well below 2  ^∘ C, as used by the IPCC in the Fifth Assessment Report, do not consider the climate impacts already occurring below 2  ^∘ C.
Anselm Schultes, Franziska Piontek, Bjoern Soergel, Joeri Rogelj, Lavinia Baumstark, Elmar Kriegler, Ottmar Edenhofer, Gunnar Luderer   +7 more
doaj   +1 more source