Results 41 to 50 of about 7,527,455 (262)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Male caregivers: a scoping review of impacts, needs, challenges, and best practices

Discover Health Systems
Although they play a crucial role in care trajectories and the quality of life of those they support, male caregivers (MCs) remain largely unrecognized, and the services available to assist them remain often insufficient or inadequate.
Bertine Sandra Akouamba, Sophie Audette-Chapdelaine, Ionela Gheorghiu, Hinatea Lai, Maggy Wassef, Adrian Mares, Walter Marcantoni   +6 more
doaj   +1 more source

Integrated assessment of marine biodiversity status using a prototype indicator-based assessment tool [PDF]

, 2014
Integrated assessment of the status of marine biodiversity is and has been problematic compared to, for example, assessments of eutrophication and contamination status, mostly as a consequence of the fact that monitoring of marine habitats, communities ...
Ciarán eMurray, Samuli Korpinen, Rindorf, Anna, Andersen, Jesper H, Henrik eSkov, Göke, Cordula, Anna eRindorf, Morten eVinther, Ciarán Murray, Martin Hartvig, Martin eHartvig, Karsten Dahl, Andersen, Jesper Harbo, Murray, Ciarán, Jesper H. Andersen, Dahl, Karsten, Cordula eGöke, Andersen, Jesper H., Samuli eKorpinen, Henrik Skov, Karsten eDahl, Korpinen, Samuli, Cordula Göke, Skov, Henrik, Vinther, Morten, Morten Vinther, Anna Rindorf, Hartvig, Martin   +27 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Animal geolocation with convolution algorithms in Julia and R via Wahoo.jl

Methods in Ecology and Evolution
Animal geolocation is the core of movement ecology. In aquatic ecosystems, electronic tagging and tracking technologies, such as passive acoustic telemetry systems and biologging sensors, are widely deployed. However, statistical estimation of individual
Edward Lavender, Carlo Albert, Andreas Scheidegger   +2 more
doaj   +1 more source

Piling up or Packaging Policies? An Ex-Post Analysis of Modal Shift in Four Cities

Energies, 2018
Recently, there has been wider acknowledgement that sustainable urban mobility will not be triggered by one ‘silver bullet’ policy, or by piling up various policies, but requires a deliberate package of policies.
Marc Dijk, Moshe Givoni, Karen Diederiks
doaj   +1 more source

Assessing policy options for sustainable water use in India’s cereal production system

Environmental Research Letters, 2023
In India, the production of rice and wheat account for more than 80% of its total agricultural water use. As farming is highly dependent on water availability, rapidly receding water levels require urgent measures to manage withdrawals.
Vartika Singh, Miodrag Stevanović, Chandan Kumar Jha, Felicitas Beier, Ranjan Kumar Ghosh, Hermann Lotze-Campen, Alexander Popp   +6 more
doaj   +1 more source