Results 101 to 110 of about 8,967,918 (378)

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Building enabled communities in Singapore

International Journal of Integrated Care, 2019
Introduction: This paper compiled the best practices in building enabled communities by six not-for-profit organisations for the elderly which were geographically distributed throughout the country.
Caroline Lim, Ivan Lim, Siang-jye Chern
doaj   +1 more source

Quality of integrated chronic care measured by patient survey: identification, selection and application of most appropriate instruments\ud [PDF]

, 2009
Objective  To identify the most appropriate generic instrument to measure experience and/or satisfaction of people receiving integrated chronic care.\ud \ud Background  Health care is becoming more user-centred and, as a result, the experience of users ...
Berbee, Rieneke, Steuten, Lotte M.G., Vrijhoef, Hubertus J.M., Wagner, Edward H.   +3 more
core   +3 more sources

The community-based integrated care system in Japan: Health care and nursing care challenges posed by super-aged society.

BioScience Trends, 2019
Japan is experiencing unprecedented aging of its population. People age 65 years or older accounted for 28.1% of the total population in 2018, and that proportion is expected to reach 33.3% in 2036 and 38.4% in 2065.
P. Song, W. Tang
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Axillary vascular malformation visualized on mammogram: A case report

Radiology Case Reports, 2022
Chest wall lesions can mimic masses on mammograms and can cause diagnostic difficulty in interpretation. Here, we report a case of an axillary and retro-pectoral vascular malformation visualized on mammography in a 67-year-old patient presenting with ...
Pranjali Joshi, MBBS, MD, Anamika Kumar, MBBS, MD, DNB, Satish Chaitanya, MBBS, MS, Prateek Sharda, MBBS, MS, Bina Ravi, MBBS, MS, MNAMS,FACS,FICS,FRCS, Anjum Syed, MBBS, MD, FRCR   +5 more
doaj  

Montefiore Medical Center: Integrated Care Delivery for Vulnerable Populations [PDF]

, 2010
Describes a system of hospitals and community- and school-based clinics tailored to low-income patients through systemwide strategies, high-quality specialty and hospital care, and integrated care delivery via care management and information ...
Deborah Chase
core  

Strengthening Integrated Primary Health Care in Sofala, Mozambique [PDF]

, 2013
Background: Large increases in health sector investment and policies favoring upgrading and expanding the public sector health network have prioritized maternal and child health in Mozambique and, over the past decade, Mozambique has achieved substantial
Alusio Pio, Cathy Michel, Fatima Cuembelo, James Pfeiffer, Joao Luis Manuel, Kenneth Sherr, Marina Kariaganis, Mark Micek, Sarah Gimbel, Stephen Gloyd   +9 more
core   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

What makes patients in primary care complex? A scoping review combined with a focus group analysis

Scandinavian Journal of Primary Health Care
Background Consultations can be challenging because of patient complexity, affecting care quality. Patient complexity involves factors related to the patient, healthcare professional, organization, and healthcare system. A comprehensive overview of these
Jozé Braspenning, Rachel van den Kieboom, Erik W.M.A. Bischoff, Kirsten Hietland, Kris Vissers, Yvonne Schoon   +5 more
doaj   +1 more source