Results 121 to 130 of about 801,972 (259)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Improving the perioperative pathway of patients with diabetes undergoing surgery – a quality improvement project

BJA Open, 2022
Shalini Saini, Tomide Owomoyela, Anand Kulkarni, Edward Jude   +3 more
doaj   +1 more source

Integrated care for chronic respiratory disease: a narrative review. [PDF]

Eur Respir Rev
Steiner MC, Ryan L, Valero-Sanchez I, Umerah O, Ward TJC.   +4 more
europepmc   +1 more source

Integrated care pathways: a new approach for integrated care systems

British Journal of General Practice, 2023
Christina van der Feltz-Cornelis, Emily Attree, Mel Heightman, Mark Gabbay, Gail Allsopp   +4 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Integrated care is necessary, but not sufficient, for equity in hepatocellular carcinoma outcomes. [PDF]

Liver Transpl
Hatipoglu D, Mahmud N.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Towards proactive, integrated care across boundaries: panel management next level. [PDF]

Fam Med Community Health
de Boer AW, Numans ME, Vos HMM, De Bruin J, Kist JM, Vos RC.   +5 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Participatory Rapid Appraisal and Focus Groups to co-design technology-supported integrated care. [PDF]

PLoS One
Sullivan BO, Davis P, Connolly R, Hanlon SO, Hamaker M, Wilders H, Kenis C, Kearns U, Corrigan T, White C, Lehn E, Gros M, Ferrara L, Ardito V, Fourrier C, Soubeyron P, Rostoft S, Thevenet V, Staines A.   +18 more
europepmc   +1 more source