Results 91 to 100 of about 214,412 (248)

Living beyond placenta accreta spectrum: parent's experience of the postnatal journey and recommendations for an integrated care pathway. [PDF]

BMC Pregnancy Childbirth, 2022
Bartels HC, Horsch A, Cooney N, Brennan DJ, Lalor JG.   +4 more
europepmc   +1 more source

ESVM integrated care pathways – a call for action [PDF]

Vasa, 2019
Vison A., Pesavento R., Mazzolai L., Cimminiello C., P'csv'rady Z., Olinic D., Johansson E., Belch J., Boc V., Brodmann M., Carpentier P. H., Chraim A., Colgan M. -P., Dimakakos E., Gotts'ter A., Heiss C., Madaric J., Poredo P., Quere I., Roztocil K., Stanek A., Vasic D., Wautrecht J. -C.   +22 more
openaire   +5 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Evaluation of an integrated care pathway for out-of-hospital treatment of older adults with an acute moderate-to-severe lower respiratory tract infection or pneumonia: protocol of a mixed methods study. [PDF]

BMJ Open, 2023
Roos R, Pepping RMC, van Aken MO, Labots G, Lahdidioui A, van den Berg JMW, Kolfschoten NE, Pasha SM, Ten Holder JT, Mollink SM, van den Bos F, Kant J, Kroon I, Vos RC, Numans ME, van Nieuwkoop C.   +15 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A cost-effectiveness study of cost of care and health consequences for two modes of treatment for patients with hip fractures

International Journal of Integrated Care, 2008
Lars-Eric Olsson, Elisabeth Hansson, Inger Ekman, Jón Karlsson   +3 more
doaj   +3 more sources

Evaluation of the impact of an integrated care pathway for pulmonary embolism: a quasi-experimental pre-post study. [PDF]

J Thorac Dis, 2021
Rodríguez-Núñez N, Ruano-Raviña A, Lama A, Ferreiro L, Ricoy J, Álvarez-Dobaño JM, Suárez-Antelo J, Toubes ME, Rábade C, Golpe A, Riveiro V, Casal A, Abelleira R, González-Barcala FJ, González-Juanatey JR, Valdés L.   +15 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The Geriatric Hearcare Services as an example of integrated ‘pathway’ in case- and care management

International Journal of Integrated Care, 2009
Michael Lerch, Mechthild Decker-Maruska
doaj   +3 more sources